ID F9F2J9_FUSOF Unreviewed; 435 AA.
AC F9F2J9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=FAD-binding domain-containing protein {ECO:0000259|Pfam:PF01494};
GN ORFNames=FOXB_00623 {ECO:0000313|EMBL:EGU88879.1};
OS Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660025 {ECO:0000313|EMBL:EGU88879.1};
RN [1] {ECO:0000313|EMBL:EGU88879.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo5176 {ECO:0000313|EMBL:EGU88879.1};
RX PubMed=21942452; DOI=10.1094/mpmi-08-11-0212;
RA Thatcher L.F., Gardiner D.M., Kazan K., Manners J.;
RT "A highly conserved effector in Fusarium oxysporum is required for full
RT virulence on Arabidopsis.";
RL Mol. Plant Microbe Interact. 25:180-190(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGU88879.1}.
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DR EMBL; AFQF01000176; EGU88879.1; -; Genomic_DNA.
DR AlphaFoldDB; F9F2J9; -.
DR STRING; 660025.F9F2J9; -.
DR PaxDb; 5507-FOXG_15312P0; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR46720; HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED; 1.
DR PANTHER; PTHR46720:SF3; HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..380
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 435 AA; 48174 MW; B2D33B61758B3FE0 CRC64;
MAKPSRNEIH VAIIGAGIGG LALAMALHKK DISFTLYEDA KEYSAVGAGI GFAPNGMRTM
DLIEPGFRPF YEAICVGNKG EKAQDIFFEG MLLEEGLGRD KPWYGHSGWG HPDYIRKSAH
RKTLLDIMTS FIPIENVKFN KRLTNIEQRP DGVTLSFLDG TTAECSVLAG ADGIKSTVRA
NVLEQYPSQI APVYAGAYCY RAVIPMSEAY EILGDLTDVA KFYFGPKRSA VTYRITGGDE
FNYLLCVADS PDGWKLKGAV TEAISHEAMM ADFEGPGVDD RFRQLLAKAK PVKWGFFHHF
RTASYYRDRV ALVGDSAHAS LPFQAAGAAQ GLEDALVLSN VLAEVAKIPE RGAELAPFIQ
AGLSAYDSVR RPRAQKQLEQ AAEVGRMIFF QHEEAGDDMD KILPRLQQGR FNWLWFHDMN
DDAQEAVKRM QKEIS
//
