ID F9F771_FUSOF Unreviewed; 505 AA.
AC F9F771;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=GTP cyclohydrolase II {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOXB_02246 {ECO:0000313|EMBL:EGU87264.1};
OS Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660025 {ECO:0000313|EMBL:EGU87264.1};
RN [1] {ECO:0000313|EMBL:EGU87264.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo5176 {ECO:0000313|EMBL:EGU87264.1};
RX PubMed=21942452; DOI=10.1094/mpmi-08-11-0212;
RA Thatcher L.F., Gardiner D.M., Kazan K., Manners J.;
RT "A highly conserved effector in Fusarium oxysporum is required for full
RT virulence on Arabidopsis.";
RL Mol. Plant Microbe Interact. 25:180-190(2012).
CC -!- SIMILARITY: Belongs to the GTP cyclohydrolase II family.
CC {ECO:0000256|ARBA:ARBA00008131}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGU87264.1}.
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DR EMBL; AFQF01000696; EGU87264.1; -; Genomic_DNA.
DR AlphaFoldDB; F9F771; -.
DR STRING; 660025.F9F771; -.
DR PaxDb; 5507-FOXG_01416P0; -.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003935; F:GTP cyclohydrolase II activity; IEA:InterPro.
DR GO; GO:0009231; P:riboflavin biosynthetic process; IEA:InterPro.
DR CDD; cd00641; GTP_cyclohydro2; 1.
DR Gene3D; 3.40.50.10990; GTP cyclohydrolase II; 1.
DR InterPro; IPR022163; GTP_CH_N.
DR InterPro; IPR032677; GTP_cyclohydro_II.
DR InterPro; IPR000926; RibA.
DR InterPro; IPR036144; RibA-like_sf.
DR PANTHER; PTHR47259; -; 1.
DR PANTHER; PTHR47259:SF2; URACIL-REGULATED PROTEIN 1; 1.
DR Pfam; PF12471; GTP_CH_N; 1.
DR Pfam; PF00925; GTP_cyclohydro2; 1.
DR SUPFAM; SSF142695; RibA-like; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 94..286
FT /note="GTP cyclohydrolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12471"
FT DOMAIN 327..460
FT /note="GTP cyclohydrolase II"
FT /evidence="ECO:0000259|Pfam:PF00925"
FT REGION 34..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 55591 MW; 559CC2FA08A624AA CRC64;
MASDDQQSSM LEALQEIQRT QALLVNAVES LSGRSIEESG GDVGKNTILE PGSREDDNEG
GTPSVEVPAA SGDKLKAPAL PSSEQRQQQG FTSRIILTTY PKQIGINPLP MDWGNQDPVK
RGPIVVSRAA STIRRRNAVG AHGGSYSIYY ALAVASNELN ADHRPDFTNT EPAANIGPFP
QWGDPKKIVA MDPWGHLAPW LFKDTIEKDN VDIRPTIAIT KAHMKLPELA ESVKAGRLVP
DGKVCLNDQG ELAVTKFAVE PVWYLPGVAE RFGIDEATLR RSLFEHTGGS YPELITRGDI
KVFLPPIGGL TVYCFGDPAK MSDESVRLSL RIHDECNGSD VFGSDICTCR PYLIFGIEEA
VKEAQNGGSG VVIYFRKEGR ALGEVTKYLV YNARKRGADR ASDYFKRTEN IAGVKDMRFQ
ALMPDILHWL GIKKIDRMLS MSNMKHDAIV GQGIPIHERV ELPEELIPAD SRVEIDAKIT
AGYFTTGKRM TTEELQAVQG RIWEE
//
