ID F9FZ44_FUSOF Unreviewed; 377 AA.
AC F9FZ44;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=FOXB_11681 {ECO:0000313|EMBL:EGU77817.1};
OS Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660025 {ECO:0000313|EMBL:EGU77817.1};
RN [1] {ECO:0000313|EMBL:EGU77817.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo5176 {ECO:0000313|EMBL:EGU77817.1};
RX PubMed=21942452; DOI=10.1094/mpmi-08-11-0212;
RA Thatcher L.F., Gardiner D.M., Kazan K., Manners J.;
RT "A highly conserved effector in Fusarium oxysporum is required for full
RT virulence on Arabidopsis.";
RL Mol. Plant Microbe Interact. 25:180-190(2012).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGU77817.1}.
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DR EMBL; AFQF01002925; EGU77817.1; -; Genomic_DNA.
DR AlphaFoldDB; F9FZ44; -.
DR STRING; 660025.F9FZ44; -.
DR PaxDb; 5507-FOXG_00186P0; -.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
FT DOMAIN 15..286
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 377 AA; 41330 MW; 440D1DBAF7C0A359 CRC64;
MAEKTKSRGP LGRVVVIGGN GFLGHHIVNQ ALEQWTTTAT IGVDLRCERN RNPNAEYREC
DITDPERLLS LFEELKPDVV IHTASPVAVN PNIGHDVFKK VNVDGTQAVV DACQKTGVKV
LVYTSSASVI SDNVTDLLNA DERWPLIRGE AQTEYYSETK AQAEEIVLKA NRQEGCKLLT
TSIRPAGIFG EGDVQTLAGI LNAYKRGKHT IQVGANENLF DFTYVGNVAH AHLLAAQLLL
ATAASPTIPL DHERVDGEAF FITNDTPVYF WDFARAIWRA AGYEKGTDGN WGLNREVGIA
IGYVSEVLAN ILGKTPTLTR KSIIMSCMTR YYNINKAKRA LRYQPVWSLK EGIDRGVNWF
LEQDKAAAAA AAAAAKA
//
