ID   F9HHI8_9STRE            Unreviewed;       674 AA.
AC   F9HHI8;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 {ECO:0000313|EMBL:EGP66083.1};
GN   ORFNames=HMPREF9182_1830 {ECO:0000313|EMBL:EGP66083.1};
OS   Streptococcus sp. oral taxon 056 str. F0418.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=904294 {ECO:0000313|EMBL:EGP66083.1, ECO:0000313|Proteomes:UP000004514};
RN   [1] {ECO:0000313|Proteomes:UP000004514}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0418 {ECO:0000313|Proteomes:UP000004514};
RA   Durkin A.S., Kim M., Radune D., Hostetler J., Torralba M., Gillis M.,
RA   Methe B., Sutton G., Nelson K.E.;
RT   "Complete sequence of Bifidobacterium breves ACS-071-V-Sch8b.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGP66083.1}.
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DR   EMBL; AFQU01000001; EGP66083.1; -; Genomic_DNA.
DR   AlphaFoldDB; F9HHI8; -.
DR   eggNOG; COG1762; Bacteria.
DR   eggNOG; COG3711; Bacteria.
DR   Proteomes; UP000004514; Unassembled WGS sequence.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd05568; PTS_IIB_bgl_like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.1790.10; PRD domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR007737; Mga_HTH.
DR   InterPro; IPR011608; PRD.
DR   InterPro; IPR036634; PRD_sf.
DR   InterPro; IPR016152; PTrfase/Anion_transptr.
DR   InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR   InterPro; IPR036095; PTS_EIIB-like_sf.
DR   InterPro; IPR013011; PTS_EIIB_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR30185; CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR; 1.
DR   PANTHER; PTHR30185:SF18; TRANSCRIPTIONAL REGULATOR MTLR; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   Pfam; PF05043; Mga; 1.
DR   Pfam; PF00874; PRD; 2.
DR   Pfam; PF00359; PTS_EIIA_2; 1.
DR   SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR   SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR   SUPFAM; SSF63520; PTS-regulatory domain, PRD; 2.
DR   PROSITE; PS51372; PRD_2; 2.
DR   PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR   PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:EGP66083.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004514};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          198..304
FT                   /note="PRD"
FT                   /evidence="ECO:0000259|PROSITE:PS51372"
FT   DOMAIN          309..416
FT                   /note="PRD"
FT                   /evidence="ECO:0000259|PROSITE:PS51372"
FT   DOMAIN          419..511
FT                   /note="PTS EIIB type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51099"
FT   DOMAIN          530..673
FT                   /note="PTS EIIA type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51094"
SQ   SEQUENCE   674 AA;  78235 MW;  09F26733A420766A CRC64;
     MTTDFVKKED KCFASKRKII LQYLMDNADQ YITSMELATH LTCSDRTVRN YLKSLIGMPT
     SQTGWKIIAK QGHGYRFVID NKDLYQKFLQ KEVFRETSTE AIEGIDDRYN YILNKLLFEQ
     ESIYLDDLVD ELYVSRSTLS SDFKKIRQDL AKYDLQIESK PKRGVYVTGD ECNIRRFIID
     FFFHDKFFHI LHNYIKIEVS GRPISLEELT IIVLDECREG RLKLSDFVIQ NLVIHIALSL
     KRIGEGFQIK QLDSWSMDEY REEGKIAEKI LKRVYHLTGL EFPKEEVDYI TLHLVSKGNV
     QTNKCENEDV AQQIRKQLLS VLEQRSFTHK YPFKNDFQLI EGLVAHLSTL FVRLKNHVKM
     VNPLLAEIQG QYAGILEMTG NILSAMPIFA NEKLSDDEVA YVALHFMTSL ERLKEKQKFN
     ILVICATGYG SAQMLKHRID NELGNIVRII DVIGYYEIND ECLKNIDFII SSIDLSNLVF
     NIPVFTVSIF LNSDEIREIR HKISLLKPIK NYRLEQETDV VDSDQERIFD RYFSPECFTV
     LHEVSKDQVI DSLLQRMSQG EDEQFVPQMK DLIEQRAGMS SIVFSDTVAV PHPIKAYAKG
     HKIGVALIPE GVVWSSEYPD IKLVFLPSPS IYGNEDLSSL TSKIVLLLEQ EELQEQMINC
     QTFTDFKKLF LRIR
//