ID   F9MQQ8_9FIRM            Unreviewed;       334 AA.
AC   F9MQQ8;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Hydrogenase expression/formation protein HypE {ECO:0000313|EMBL:EGS32195.1};
GN   Name=hypE {ECO:0000313|EMBL:EGS32195.1};
GN   ORFNames=HMPREF1040_0439 {ECO:0000313|EMBL:EGS32195.1};
OS   Megasphaera sp. UPII 135-E.
OC   Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC   Megasphaera.
OX   NCBI_TaxID=1000569 {ECO:0000313|EMBL:EGS32195.1, ECO:0000313|Proteomes:UP000004137};
RN   [1] {ECO:0000313|EMBL:EGS32195.1, ECO:0000313|Proteomes:UP000004137}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UPII 135-E {ECO:0000313|EMBL:EGS32195.1,
RC   ECO:0000313|Proteomes:UP000004137};
RA   Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA   Nelson K.E.;
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HypE family.
CC       {ECO:0000256|ARBA:ARBA00006243}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGS32195.1}.
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DR   EMBL; AFUG01000043; EGS32195.1; -; Genomic_DNA.
DR   RefSeq; WP_007393219.1; NZ_AFUG01000043.1.
DR   AlphaFoldDB; F9MQQ8; -.
DR   eggNOG; COG0309; Bacteria.
DR   OrthoDB; 9801934at2; -.
DR   Proteomes; UP000004137; Unassembled WGS sequence.
DR   CDD; cd02197; HypE; 1.
DR   Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR   Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 1.
DR   InterPro; IPR011854; HypE.
DR   InterPro; IPR010918; PurM-like_C_dom.
DR   InterPro; IPR036676; PurM-like_C_sf.
DR   InterPro; IPR016188; PurM-like_N.
DR   InterPro; IPR036921; PurM-like_N_sf.
DR   NCBIfam; TIGR02124; hypE; 1.
DR   PANTHER; PTHR30303:SF0; CARBAMOYL DEHYDRATASE HYPE; 1.
DR   PANTHER; PTHR30303; HYDROGENASE ISOENZYMES FORMATION PROTEIN HYPE; 1.
DR   Pfam; PF00586; AIRS; 1.
DR   Pfam; PF02769; AIRS_C; 1.
DR   PIRSF; PIRSF005644; Hdrgns_mtr_HypE; 1.
DR   SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR   SUPFAM; SSF55326; PurM N-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004137}.
FT   DOMAIN          35..148
FT                   /note="PurM-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00586"
FT   DOMAIN          160..306
FT                   /note="PurM-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02769"
SQ   SEQUENCE   334 AA;  35316 MW;  2C3283EFB50E5C1F CRC64;
     MEKFITLAHG AGGKHTSELI ESVFKAHFYN PLFTGDDAAI LPIPGEKLAF STDGFIVSPP
     DFAGGNIGKL SICGTVNDLA CMGAKPMYLS CAMVIEEGLP VEDLKRYVTS MEDTAKEVGV
     LIVAGDTKVA GKGQVDKLFI TTTGIGKVTP GLSLSGTKAK PGDVIMVTGD IGRHGCTILL
     ARNKFGIDAE ITSDCAPLWS LVDNMLKATR DIHVIRDATR GGVGTVLYEI AAQSKVGICL
     KSTAIPVHPS VRGVCGLLGL EPLYLACEGR MVIIVPEAQA MKALDTLRHS PHGEETAIIG
     RVTDELVGHV VMETEIGTKT MLPPPRGELL PRIC
//