ID F9PE30_9STRE Unreviewed; 2429 AA.
AC F9PE30;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Gram-positive signal peptide protein, YSIRK family {ECO:0000313|EMBL:EGV13183.1};
GN ORFNames=HMPREF1124_0309 {ECO:0000313|EMBL:EGV13183.1};
OS Streptococcus infantis X.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=997830 {ECO:0000313|EMBL:EGV13183.1, ECO:0000313|Proteomes:UP000003399};
RN [1] {ECO:0000313|EMBL:EGV13183.1, ECO:0000313|Proteomes:UP000003399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=X {ECO:0000313|EMBL:EGV13183.1,
RC ECO:0000313|Proteomes:UP000003399};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGV13183.1}.
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DR EMBL; AFUQ01000007; EGV13183.1; -; Genomic_DNA.
DR PATRIC; fig|997830.4.peg.1069; -.
DR eggNOG; COG3250; Bacteria.
DR eggNOG; COG3583; Bacteria.
DR Proteomes; UP000003399; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 3.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR049487; BgaA-like_CBM.
DR InterPro; IPR011081; Big_4.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR011098; G5_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR040605; Glyco_hydro2_dom5.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF21606; BgaA-like_CBM; 2.
DR Pfam; PF07532; Big_4; 4.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF07501; G5; 1.
DR Pfam; PF18565; Glyco_hydro2_C5; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01208; G5; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS51109; G5; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..38
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 39..2429
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003385246"
FT DOMAIN 2138..2220
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 2396..2429
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 65..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2364..2401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2367..2388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2429 AA; 267233 MW; 122D800C6D4D79AC CRC64;
MDKRFFEKRC HFSIRKFAIG AASVMIGASI FGLQVAQAAE TETSSTTEET IHQVQPLDKL
PDDLAAAIAK AEQNGPQDSA TEKEEKDTDE AAKPVTEDKV TEETSPKKEK EVEVVSPKEE
ITEKPAAEVN EKEPTVAEVN TEKPAVLEEH TAEANQNKPV SDDKAKEEKI SATDLPQVTK
EKEKEDQLLQ ERKQNFNKDW YFKLNAQGDF SKKDVDVHDW SKLNLPHDWS IYFDFDHKSP
ARNEGGQLNG GTAWYRKTFT VDEAAKDKDV RINFDGVYMD SKVYVNGKFV GHYPSGYNHF
SYDITEFLNK DGSENTIAVQ VTNKQPSSRW YSGSGIYRDV TLSYRDKVQV AENGNHITTP
KLAQQKDGNV ETQIQSKIKN TAKTLAKVFV EQQIFTKEGK AVSDLVRSVT KNLAGNEAAD
FKQTILVNKP TLWTTKSYNP QLYVLKTKVY NEGQLVDVTE DTFGYRYFNW TAKEGFSLNG
ERMKFHGVSI HHDNGALGAE ENYKATYRKL KLLKDMGVNS IRTTHNPASP QLLDAAASLG
LLVQEEAFDT WYRGKKTYDY GRFFDQDATH PEAKKGEKWS DFDLRTMVER DKNNPSIIMW
SLGNEVDEAD GGERSLETAK RLKAVIKAID TERYVTMGEN KFSRASTGLF LKLAAIMDAV
GMNYGERFYD AVRKAHPDWL IYGSETSSAT RTRDSYFYPA KNLYHDNRPN RHYEQSDYGN
DRVAWGRTAT ESWTFDRDRA GYAGQFIWTG FDYIGEPTPW HNQDHTPVKS SYFGIIDTAG
LPKNDFYLYR SEWYSAKEKP TVRIMPHWNW TDETLKERNM LINGKVPVRT FSNAASVELF
LNNESLGKKE FTKKTTADGR PYHEGANPGE LYLEWLVEYK PGTLTAIARD ENGKEIARDS
VTTAGEPARV RLTKEEHVIT ADGKDLSYIH YEIVDEDGNV VPTANNLVHF NLHGQGQIVG
VDNGEQASRE RYKAQKDGTW QRKAFNGKGV VIVKSTEKEG KFTLYADSAG LASDQATVTT
VSGKKENRHF VAFAPVKATT DVSENPKLPK TVTAIYSDGS VEEKSVTWDI PDDLLTSAGE
KKVLGSVEGL EAKAEALVKV IALDKWLPKV ATVPVGTATE DLDKTVTAVL SDGNLVDADV
VSWTLKDPSA LTKEGGRTEA TGKLVGNDYE VTATFIASDQ ETENTVTGLT VGDKALADFE
PGKTYYRVSL PYSAKIPSVG AQARGYQVTV QQASAANDYQ ASVFLSDQKG DLVQTYLIQF
VKEAPALTRL EVSVEGKENA TEDQVLPYHV IGHYEDGSQT EFSASDIHLD ASSTDGGHLE
VNGQNLLLYT KGSVTLTPRI EHQTEKTQSV ATVVVIKENK VAKKIVKLHP VSISTDINQQ
PNLPDQIGAE FDKGLPRKLA VTWDKVDEKE LASYHSFTLK GHVEGTDIEA VANVTVEGLQ
VAEEISLTLP KGETVQLPAN VRAYHSNGTT VYNDVVWDKV PANFSQTEGI FEIKGQLVGS
SLTTKAHVRV SSQVVAGNNI SKQWTGSQLP AAIVSNTGGD DSANTLNDLT VSRANTDVKN
RWTTWQTNTD NDWASILFGN SGDLTKRFVD NLSVDFYTDG AIGLPKEYVI EYYVGQEIPD
LPTDVNHAQG DANHPFNNAA NWKEVEHLKA PGQLSASQTN HFTFDKVETY AVRIRMKKAN
GTDGVGLTEI TILGNKVPSA TSSEISIRVD GQKLEHFNPA KTDYHIPQAS KVITATASDN
GLVTIVPATS PEGATRLILK AEDGTILKEY RIFRDGQKES TQPVAAENAA MTLSVGDKLQ
LPTEVTVYYP SETDWTRDKL AVEWDAVPEH ATDQEGTFEV LGHILGTDLT TKMQVTVLAR
GNQVISENTS NNATDSKAFA STTNDTDAAS NDRIFYINDG RFNEDGRWTN WSRTPKNQEV
SVGVLFKKNG QITPRSVGKV AIQFFKDSGT DAPATMVLER YVGPVYSEPS TISRYEENAD
HPFNKAENWQ EIPYKASGAI EAGKPIEFTF DPIQTTAIRA RMTRKSTTNG LAMVEFSAYS
PAKASDSETP AVTISVAGKA LENFDPAVSE YRLTANGAKP EVTVQTSGHG VATVVESNQG
NLPTLVRLLA KDGSLVKEYR LHFEAGSEAS HAVDDQALVL DRPSLEVEKA VIPFKEIIRE
NSDLAKDERR IVSVGQNGEK VDYVEVLGTS RKVVHTETIE AKDQIVEVGV KAVATSSKGE
EPAPVLEIPE YTDPIGTVGE EPAPIVEVPE YSNSIGTAGD QAAPVLEVPE FKGGANWVEA
ATNEVPEFKG GANWVEAAKN EVPEFKGGAN WVEAATNEVP EFKGGANAVQ ADKNELPEYT
GTLGTAGDQA APTIDKPVAD IRGLSDKPSE TQASAEQTQV SQVLGNASEK AVSARLPETG
ESQSDTAIFL AGLSLALSAA FLNGKRKEE
//
