ID   F9Q3S8_STROR            Unreviewed;       444 AA.
AC   F9Q3S8;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=Xanthine permease {ECO:0000313|EMBL:EGV01201.1};
GN   Name=pbuX {ECO:0000313|EMBL:EGV01201.1};
GN   ORFNames=HMPREF9950_0262 {ECO:0000313|EMBL:EGV01201.1};
OS   Streptococcus oralis SK313.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1035190 {ECO:0000313|EMBL:EGV01201.1, ECO:0000313|Proteomes:UP000005621};
RN   [1] {ECO:0000313|EMBL:EGV01201.1, ECO:0000313|Proteomes:UP000005621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK313 {ECO:0000313|EMBL:EGV01201.1,
RC   ECO:0000313|Proteomes:UP000005621};
RA   Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA   Nelson K.E.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGV01201.1}.
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DR   EMBL; AFUU01000004; EGV01201.1; -; Genomic_DNA.
DR   AlphaFoldDB; F9Q3S8; -.
DR   PATRIC; fig|1035190.4.peg.1403; -.
DR   Proteomes; UP000005621; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR017588; UacT-like.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   NCBIfam; NF037981; NCS2_1; 1.
DR   NCBIfam; TIGR03173; pbuX; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        42..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        67..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        123..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        337..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        393..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        427..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   444 AA;  47034 MW;  9041EB4A54FAC741 CRC64;
     MQKQEKHSQA AVLGLQHLLA MYSGSILVPI MIATALGYSA EQLTYLISTD IFMCGVATFL
     QLQLNKYFGI GLPVVLGVAF QSVAPLIMIG QSHGSGAMFG ALIVSGIYVV LISGIFSKVA
     NLFPSIVTGS VITTIGLTLI PVAIGNMGNN VPEPTGQSLL LAAITVLIIL LINIFTKGFI
     KSISILIGLV VGTAIAATMG LVDFSPVAAA PLVHVPTPLY FGVPTFEISS IVMMCIIATV
     SMVESTGVYL ALSDITNDPI DSTRLRNGYR AEGLAVLLGG IFNTFPYTGF SQNVGLVKLS
     GIKTRLPIYY AAGFLVLLGL LPKFGALAQI IPSPVLGGAM LVMFGFVSLQ GMQILARVDF
     ANNEHNFLIA AVSIAAGVGL NNSNLFVSMP TAFQMFFSNG IVVASLLAIV LNAVLNRKRN
     KKKRCEPLFC FFISLPVFLL TFVL
//