GenomeNet

Database: UniProt
Entry: F9VI26_ARTSS
LinkDB: F9VI26_ARTSS
Original site: F9VI26_ARTSS 
ID   F9VI26_ARTSS            Unreviewed;       452 AA.
AC   F9VI26;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   05-JUL-2017, entry version 43.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:BAK55784.1};
GN   OrderedLocusNames=SFBM_0001 {ECO:0000313|EMBL:BAK55784.1};
OS   Arthromitus sp. (strain SFB-mouse-Japan).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Candidatus Arthromitus.
OX   NCBI_TaxID=1029718 {ECO:0000313|EMBL:BAK55784.1, ECO:0000313|Proteomes:UP000001636};
RN   [1] {ECO:0000313|EMBL:BAK55784.1, ECO:0000313|Proteomes:UP000001636}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SFB-mouse-Japan {ECO:0000313|Proteomes:UP000001636};
RX   PubMed=21791478; DOI=10.1093/dnares/dsr022;
RA   Kuwahara T., Ogura Y., Oshima K., Kurokawa K., Ooka T., Hirakawa H.,
RA   Itoh T., Nakayama-Imaohji H., Ichimura M., Itoh K., Ishifune C.,
RA   Maekawa Y., Yasutomo K., Hattori M., Hayashi T.;
RT   "The lifestyle of the segmented filamentous bacterium: a non-
RT   culturable gut-associated immunostimulating microbe inferred by whole-
RT   genome sequencing.";
RL   DNA Res. 18:291-303(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AP012202; BAK55784.1; -; Genomic_DNA.
DR   RefSeq; WP_007439964.1; NC_015913.1.
DR   STRING; 1029718.SFBM_0001; -.
DR   EnsemblBacteria; BAK55784; BAK55784; SFBM_0001.
DR   KEGG; asf:SFBM_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001636; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001636};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001636}.
FT   DOMAIN      146    274       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      358    427       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     154    161       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   452 AA;  51832 MW;  D9A83993E2ED5E6E CRC64;
     MEFNYNDLWN DILLELKKSL SDISFNTWFS DVKILNIYNS NIIIGCNNSL ISETINLRYL
     DSLTSIIFNL TKQHYTVKCI LKDSFKSEYS KDLNKTITLS AHDNVLNTAL SSNLNSKYTF
     ETFVVGNSNR FAHAASLAVA ESPSKAYNPL FIYGGVGLGK THLMHAIGHL INENNSNLKV
     VYVTSEKFIN ELISAIKDDK NIEFRDKYRT VDVLLIDDVQ FIAGKERTQE EFFHTFNSLH
     ESNKQIILSS DRPPKEIKTL EERLRSRFEW GLIADIQPPD YETRIAILRK KADVDKLNVP
     NEVLIYIATK IKSNIRELEG ALLRVVAYTN LTNSNISLEL AKEALKDLIN IKNSKIITIE
     YIQETISNYF DLTIDIIKSQ RRTQNIAFPR QIAMYLCRKL TDSSLPKIGE KFGGRDHTTV
     IHAYEKILNK IESDPEFNNL IIELSNKITN NK
//
DBGET integrated database retrieval system