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Database: UniProt
Entry: F9W8H3_TRYCI
LinkDB: F9W8H3_TRYCI
Original site: F9W8H3_TRYCI 
ID   F9W8H3_TRYCI            Unreviewed;       451 AA.
AC   F9W8H3;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   22-NOV-2017, entry version 21.
DE   SubName: Full=WGS project CAEQ00000000 data, annotated contig 1735 {ECO:0000313|EMBL:CCD13505.1};
GN   ORFNames=TCIL3000_0_42510 {ECO:0000313|EMBL:CCD13505.1};
OS   Trypanosoma congolense (strain IL3000).
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma;
OC   Nannomonas.
OX   NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCD13505.1, ECO:0000313|Proteomes:UP000000702};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL3000;
RA   Jackson A.P., Berry A., Allison H.C., Burton P., Anderson J.,
RA   Aslett M., Brown R., Corton N., Harris D., Hauser H., Gamble J.,
RA   Gilderthorp R., McQuillan J., Quail M.A., Sanders M., van Tonder A.,
RA   Ginger M.L., Donelson J.E., Field M.C., Barry J.D., Berriman M.,
RA   Hertz-Fowler C.;
RT   "Divergent evolution of antigenic variation in African trypanosomes.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000000702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL3000 {ECO:0000313|Proteomes:UP000000702};
RA   Jackson A.P., Berry A., Allison H.C., Burton P., Anderson J.,
RA   Aslett M., Brown R., Corton N., Harris D., Hauser H., Gamble J.,
RA   Gilderthorp R., McQuillan J., Quail M.A., Sanders M., Van Tonder A.,
RA   Ginger M.L., Donelson J.E., Field M.C., Barry J.D., Berriman M.,
RA   Hertz-Fowler C.;
RT   "Divergent evolution of antigenic variation in African trypanosomes.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:CCD13505.1, ECO:0000313|Proteomes:UP000000702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL3000 {ECO:0000313|EMBL:CCD13505.1,
RC   ECO:0000313|Proteomes:UP000000702};
RX   PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA   Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA   Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H.,
RA   Gamble J., Gilderthorp R., Marcello L., McQuillan J., Otto T.D.,
RA   Quail M.A., Sanders M.J., van Tonder A., Ginger M.L., Field M.C.,
RA   Barry J.D., Hertz-Fowler C., Berriman M.;
RT   "Antigenic diversity is generated by distinct evolutionary mechanisms
RT   in African trypanosome species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC   -!- SIMILARITY: Belongs to the peptidase M18 family.
CC       {ECO:0000256|RuleBase:RU004386}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCD13505.1}.
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DR   EMBL; CAEQ01001170; CCD13505.1; -; Genomic_DNA.
DR   MEROPS; M18.002; -.
DR   Proteomes; UP000000702; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR001948; Peptidase_M18.
DR   InterPro; IPR023367; Peptidase_M42_dom2.
DR   PANTHER; PTHR28570; PTHR28570; 1.
DR   Pfam; PF02127; Peptidase_M18; 1.
DR   PRINTS; PR00932; AMINO1PTASE.
DR   SUPFAM; SSF101821; SSF101821; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|RuleBase:RU004386};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000702};
KW   Hydrolase {ECO:0000256|RuleBase:RU004386};
KW   Metal-binding {ECO:0000256|RuleBase:RU004386};
KW   Metalloprotease {ECO:0000256|RuleBase:RU004386};
KW   Protease {ECO:0000256|RuleBase:RU004386};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000702};
KW   Zinc {ECO:0000256|RuleBase:RU004386}.
SQ   SEQUENCE   451 AA;  49245 MW;  5C457F0C002F8580 CRC64;
     MLPISTPAAK ELAKEFVDFI KEACTPFHAV EVLSSWLLKA GYNRLQEGEV WPKLLNGGKY
     FVTRNDSSLI AFAVGGKFES NNGLKIIGAH TDSPNLALKP RSKAGKGDYK GVAVQCYGGG
     LWHTWFDRDL TVAGRVFISS SNLEKRLVKL NRPIMRIPTL AIHLQSTEER NAFGPNKEKH
     LVPIIATALT ESQDDKVSEH HNSHLLTLLA ESLGCEPNEI VDYDLSVIDT QEPVVGGACD
     EFIYAPRLDN LISCFCGVKA LLEADSSLDQ DDMIRMVCLF DNEEIGSATS QGAGGSFVPD
     VIEHITSCGG LRATLVANSF LLSIDGSHAV HPNYQEKHED NHRPLLHRGP VIKYNANMRY
     ATNGATAAVI KSIAKKASVP IQEFCVKNDS PCGSTIGPIL SSLSGVQTID IGNPMLSMHS
     IREMCGTIDL LYLKNLVEAF FNQYKSCTVA R
//
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