ID F9WS01_TRYVY Unreviewed; 316 AA.
AC F9WS01;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 13-SEP-2023, entry version 29.
DE RecName: Full=MGT2 magnesium transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=TvY486_0031265 {ECO:0000313|EMBL:CCD20338.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCD20338.1, ECO:0000313|Proteomes:UP000009027};
RN [1] {ECO:0000313|EMBL:CCD20338.1, ECO:0000313|Proteomes:UP000009027}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCD20338.1,
RC ECO:0000313|Proteomes:UP000009027};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; CAEX01005322; CCD20338.1; -; Genomic_DNA.
DR AlphaFoldDB; F9WS01; -.
DR VEuPathDB; TriTrypDB:TvY486_0031265; -.
DR OMA; DCIDEMM; -.
DR OrthoDB; 160173at2759; -.
DR Proteomes; UP000009027; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF95; MGT2 MAGNESIUM TRANSPORTER; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009027};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 287..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 316 AA; 34483 MW; 5B641AD0560E0254 CRC64;
MQPSHADAVL ASDIHDVAEL QAGHGEYVVG CLACSRDRGG PFLSSAPTEV AGDSDEVVLC
SFACDERRLL TLHASPFVGL SEALRSAECD CPAANASSHS EGVKALSAAA LLCALVCFTC
EARLPDTTPL VTEVDCIDEM MMLVAPGKSD QTDMLRRVAL LRRRLSSTTR QLRAKEGLLQ
ELVGPTMRTS FVSRDASVVS SYREAFDELW PVLECLECAS DAVNHASLNF MYAISMRMSQ
ASAGFDYQMM IINKIVTVCL PANLLCSLFG MNCRVAWQAD EQADLRAFWG IIGLISLWLA
VCLFRPVRDF LRWRGA
//
