ID F9WZZ8_ZYMTI Unreviewed; 578 AA.
AC F9WZZ8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:EGP92460.1};
GN ORFNames=MYCGRDRAFT_34982 {ECO:0000313|EMBL:EGP92460.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP92460.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP92460.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; CM001196; EGP92460.1; -; Genomic_DNA.
DR RefSeq; XP_003857484.1; XM_003857436.1.
DR AlphaFoldDB; F9WZZ8; -.
DR STRING; 336722.F9WZZ8; -.
DR EnsemblFungi; Mycgr3T34982; Mycgr3P34982; Mycgr3G34982.
DR GeneID; 13403055; -.
DR KEGG; ztr:MYCGRDRAFT_34982; -.
DR eggNOG; KOG1238; Eukaryota.
DR HOGENOM; CLU_002865_6_3_1; -.
DR InParanoid; F9WZZ8; -.
DR OMA; PSMMNHE; -.
DR OrthoDB; 3215324at2759; -.
DR Proteomes; UP000008062; Chromosome 1.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR PANTHER; PTHR11552:SF210; GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 2.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 2.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..578
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003391041"
FT DOMAIN 269..283
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 250
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 511..512
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 578 AA; 62966 MW; F271DBA8CDDF764A CRC64;
MFTHTAPAIL LGVLSTANLV AANPPGPPYF STFQYQFAPA IDFEPSYDFC IVGGGTAGLV
LANRLTESGK HNVIVFEGGP TPDTNPTSLT GGANPYLLNG ARSLVDYNFV TQPQRNLNNR
SLPYHRGRCL GGSSATNGFF YGLGSKAVYD QWELDGNPGW NWANISAAAK RGTMFVGNPN
NTNDNTYMTW DPENYGTEGP LKVGFQGFVP ASNPAFMNAT SAIGVGVVHD QNGGSPTDSG
EQEATGLTFV EGAIWHNISC SKEVILSAGA FHSPYLLKQS GIGPRDELEE HEIPVRVENE
HVGHHMQDHT AFSVIYSIKP EFAHIASTTE KNNDLTLLNE QQRSFYNTSD PHERAKSRWS
AVSGTNAFQE ICSEDLKEFG AGAVIDAGLV SQAHNEIMYE GGWYPFFSNK YGKPRRNTSY
VSLTVSNMAA LSQGSVTVGN NMPLGDPVID PNYLNHTADI AMAIQGLKYV RKIGQHPDWQ
KWVAEEVAPG PGVQTDEEIL EYVKTVMIPN WHAASTCRML PKEKGGVVDS HLRVYGTKRL
RVCDVSTLGR LPDINLQGSV YAVAEHGARI IREEYGDL
//
