ID F9XF24_ZYMTI Unreviewed; 819 AA.
AC F9XF24;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=DUF221-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MYCGRDRAFT_45088 {ECO:0000313|EMBL:EGP85609.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP85609.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP85609.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; CM001202; EGP85609.1; -; Genomic_DNA.
DR RefSeq; XP_003850633.1; XM_003850585.1.
DR AlphaFoldDB; F9XF24; -.
DR EnsemblFungi; Mycgr3T45088; Mycgr3P45088; Mycgr3G45088.
DR GeneID; 13397974; -.
DR KEGG; ztr:MYCGRDRAFT_45088; -.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_002458_0_0_1; -.
DR InParanoid; F9XF24; -.
DR OMA; QGIGMFP; -.
DR OrthoDB; 366603at2759; -.
DR Proteomes; UP000008062; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 614..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 680..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 706..725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..186
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 206..409
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 420..697
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 273..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 819 AA; 93348 MW; 5AA487B7AF4B967C CRC64;
MGSPRDTVFQ IVFSLALGIG AFLTFCVLRP RWAGLYAARK KTKDEATVLP ELPNTLFGWI
LPLWRITDQQ LLASAGLDAY VFLAFFKLAM KFLFATLLFS LIVIKPVHDA YPEEDDDGKG
KHNKTHHDAD LFRQPGLRRS TGFDWVPKNG TEYPWDPRNF ETDYLWMYLA FAYLFSAIAV
YLIYSETRTV IEVRQEYLGT QTTVTDRTLR LSGIPQTLQD EQKVKDFIEE LDIGKVETVV
LCRNWKELDD AMAERTDIMR RLEEAYTIHL GRRRSERDTE TLPIVQPAPS GPEGESLLDA
DENGTPADDA AVPVRPFSRF RPQATIRSGW LGLRRHTVDA IDYYEEKLSE ADEKIKQLRK
KDFPPTPLAF VTMDSVAACQ MAIQAVLDPS PLQLIANQSP EPSDVIWPNT YLSRTSRMVR
SWSVTVLIVL LTVFWSIILL PIAGLFNVKT IRRVLPGLGD ILEEHGNLET IVTSQIPVLL
ASLLMVLVPY LYNWLSWYQG QISRGDIELS TISKNFFFTF FNFFIVLTVL GTGSNFYQFF
ENFGDAIRDF QRIAYTLALS LQGMLKFYVN FIILQGVGLF PFRMLEVGSV SLYPVMLMGA
KTPRDYAELV QPPVFSYGFY LPGALLIFII CMVYSVLRSS WQVLLAGWLY FAMGHFVYKY
QLLYAMDHRQ QASGRAWGMI CDRIFVGLIC FQVTTAGQLL LKQAVYRGAM MIPLIIATIW
IQIWYGRTYK PLMKFIAFTA ALERNVWADN NDASQQPGAS RRPRRQNWRE NGDIRERNLP
FINPSLVAPL GKIWIADGND REGAALVSPA EIENGESNV
//
