ID   F9ZAW5_ODOSD            Unreviewed;       872 AA.
AC   F9ZAW5;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   OrderedLocusNames=Odosp_1154 {ECO:0000313|EMBL:ADY32214.1};
OS   Odoribacter splanchnicus (strain ATCC 29572 / DSM 20712 / CIP 104287 / JCM
OS   15291 / NCTC 10825 / 1651/6) (Bacteroides splanchnicus).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Odoribacteraceae;
OC   Odoribacter.
OX   NCBI_TaxID=709991 {ECO:0000313|EMBL:ADY32214.1, ECO:0000313|Proteomes:UP000006657};
RN   [1] {ECO:0000313|EMBL:ADY32214.1, ECO:0000313|Proteomes:UP000006657}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29572 / DSM 20712 / JCM 15291 / NCTC 10825 / 1651/6
RC   {ECO:0000313|Proteomes:UP000006657};
RX   PubMed=21677857; DOI=10.4056/sigs.1714269;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Goker M., Gronow S., Zeytun A., Nolan M., Lucas S., Lapidus A., Hammon N.,
RA   Deshpande S., Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N.,
RA   Mavromatis K., Ovchinikova G., Pati A., Tapia R., Han C., Goodwin L.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Jeffries C.D., Brambilla E.M.,
RA   Rohde M., Detter J.C., Woyke T., Bristow J., Markowitz V., Hugenholtz P.,
RA   Eisen J.A., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Odoribacter splanchnicus type strain
RT   (1651/6).";
RL   Stand. Genomic Sci. 4:200-209(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|ARBA:ARBA00009922}.
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DR   EMBL; CP002544; ADY32214.1; -; Genomic_DNA.
DR   RefSeq; WP_013611435.1; NZ_CP086000.1.
DR   AlphaFoldDB; F9ZAW5; -.
DR   STRING; 709991.Odosp_1154; -.
DR   PaxDb; 709991-Odosp_1154; -.
DR   GeneID; 69856482; -.
DR   KEGG; osp:Odosp_1154; -.
DR   eggNOG; COG0210; Bacteria.
DR   HOGENOM; CLU_006494_1_1_10; -.
DR   OrthoDB; 9809039at2; -.
DR   BioCyc; OSPL709991:G1GRN-1163-MONOMER; -.
DR   Proteomes; UP000006657; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000006657}.
FT   DOMAIN          157..631
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         178..185
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   872 AA;  100827 MW;  0B25072B0C846FD3 CRC64;
     MQLVLLIVVV SLVAISVIAI VTIRIRLKNK SKELSEKLNH ISSYSNKSNY EQAKERLSAL
     NNEAFIDIPT DLNNVFSCKI ISATQEKDFT NHYIPYFQEA HSLVKRLEAF NITPSVAISN
     LIRDFGNINK IVEQHNDAVI NSLLDTHKEF FDHCLKYPLD KQQRRSIVSE EDNCLVVSSA
     GSGKTSSIVG KVKYLTEIKG IVPHRILLIS YTNKAAAELT ERMATDGLKG YTFHKLAIDI
     IGKATGTKPS ICDNTDSLFI DIYHTLLENK AFKNSVVEYF IDYQSNEADW EQRKNERREK
     LSEQKNVQLK AMFPDMDGRA IYVRSEQEQK ICFVLSSLGV KFRYEEPYEH QLADEMHSQY
     RPDFSIYFEQ AGVIKRIYLE HFGVDEHSLV PAWFAKDKNI TYEEANQKYN DGITWKKAAH
     EKFGTQLLVT SSADFHYSDI RGKLRKLLDD AGVPIQEKTD EELYDLVLPK GSKQEKAFIR
     LAVTFVTLVK SSCKSVKEVL KQAKNADDER SVFIIKNIFQ PVYERYISAL SDSNQIDFTD
     AILQATEICR TSHLVEYDYI IVDEFQDISV DRYNFLKVLR DGNPPAKLYC VGDDWQSIYR
     FSGSDMALFN QFPEYFGATE INKIETTYRF GEPLVSLSSH FIQRNKAQIQ KDIHSFSSEM
     KTELEFYSYD RRDYCNTIGQ LVASIPKNKS IFLLGRYSFD DYYLSFMYQS IKEGNRFFYV
     IGERKIEFLT VHKSKGLEAD YVILLQCNKD TYGFPSLVSD DPVLKYVLTK SDQFPYGEER
     RLFYVAITRA KMKTLVLYDK RFPSVFVDEF LHPERVSEEN YVKHPNANKR WTRGADQFLL
     KLHDEGKSVK YIAAKMGRSQ TSIVMRLNKL TQ
//