ID F9ZU25_ACICS Unreviewed; 750 AA.
AC F9ZU25;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:AEK59321.1};
GN OrderedLocusNames=Atc_2674 {ECO:0000313|EMBL:AEK59321.1};
OS Acidithiobacillus caldus (strain SM-1).
OC Bacteria; Pseudomonadota; Acidithiobacillia; Acidithiobacillales;
OC Acidithiobacillaceae; Acidithiobacillus.
OX NCBI_TaxID=990288 {ECO:0000313|EMBL:AEK59321.1, ECO:0000313|Proteomes:UP000006135};
RN [1] {ECO:0000313|EMBL:AEK59321.1, ECO:0000313|Proteomes:UP000006135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM-1 {ECO:0000313|EMBL:AEK59321.1,
RC ECO:0000313|Proteomes:UP000006135};
RX PubMed=21703548; DOI=10.1016/j.jgg.2011.04.006;
RA You X.Y., Guo X., Zheng H.J., Zhang M.J., Liu L.J., Zhu Y.Q., Zhu B.,
RA Wang S.Y., Zhao G.P., Poetsch A., Jiang C.Y., Liu S.J.;
RT "Unraveling the Acidithiobacillus caldus complete genome and its central
RT metabolisms for carbon assimilation.";
RL J. Genet. Genomics 38:243-252(2011).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CP002573; AEK59321.1; -; Genomic_DNA.
DR RefSeq; WP_004869169.1; NC_015850.1.
DR AlphaFoldDB; F9ZU25; -.
DR STRING; 990288.Atc_2674; -.
DR GeneID; 69613109; -.
DR KEGG; acu:Atc_2674; -.
DR HOGENOM; CLU_005070_4_2_6; -.
DR OrthoDB; 5287200at2; -.
DR Proteomes; UP000006135; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:AEK59321.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:AEK59321.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006135};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 147..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 83405 MW; BD6646604088B7D6 CRC64;
MIDKALEQSI NQAFQMARQY GHEYASVEHL LLALLDNPSG REVLEACGAN RSQLERDLRK
FLEEKIPSLG TAGTVNTQPS IGFQRVIQRA LYHVQSAGKD TVTGANVLVA IFAERESHAV
YFLQKEHVSR LDVVNFLAHG MRKDELVEEE EEVSSEEGQK PGKDPLSAYA RNLNAMARAG
RLDPLIGRQT EMQRALQILA RRRKNNPLFV GEPGVGKTAI VEGLARAIVQ GKVPELLEDA
TIYALDMGAL IAGSRYRGDF EERLKGVLKA LRKKPNSILF IDEIHTIIGA GAASGGAMDA
SNLLKPALAS GELKCIGATT YQEYRQYFEK DRALTRRFQK IDVPEPSAEE AVQILRGLKG
QFERHHRLRY TDSALRAAVE LSVKHIHDRH LPDKAIDLID EVGAAQSLLP PSRRKKSIGV
HDIEEMVARV ARIPGKNVSL DDRTALKNLE RDLSLVIFGQ DRAIRELSAA IKMARAGLRH
HEKPVGSFLF AGPTGVGKTE LSRQLATLLG IPLLRFDMSE YMERHTVSRL IGAPPGYVGY
DQSGQLTEAV NQHPHAVLLL DEIEKAHPDI FNVLLQVMDH GKLTDASGRS VDFRNVILIM
TTNAGADQRG KASVGFVAPA GVEEGREMES IQRIFAPEFR NRLDAVVPFA PLSREHVLHV
VDKFLMELDE QLLQKDYSLE VQPELRQWLA DRGYDPQMGA RPMARVIQEH LKKPLAEHIL
FGDLPKGTRI LAELRDGRVE IRIPEALPSS
//
