GenomeNet

Database: UniProt
Entry: FAR1_ONCGU
LinkDB: FAR1_ONCGU
Original site: FAR1_ONCGU 
ID   FAR1_ONCGU              Reviewed;         178 AA.
AC   Q8WT59;
DT   21-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-JUN-2005, sequence version 2.
DT   01-OCT-2014, entry version 31.
DE   RecName: Full=Fatty-acid and retinol-binding protein 1;
DE   AltName: Full=Og-FAR-1;
DE   Flags: Precursor;
GN   Name=far-1 {ECO:0000312|EMBL:AAL33789.1};
OS   Onchocerca gutturosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Spirurida;
OC   Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=6283;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAL33789.1}
RP   NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND GLYCOSYLATION.
RX   PubMed=12106870; DOI=10.1016/S0166-6851(02)00097-X;
RA   Garofalo A., Klager S.L., Rowlinson M.C., Nirmalan N., Klion A.D.,
RA   Allen J.E., Kennedy M.W., Bradley J.E.;
RT   "The FAR proteins of filarial nematodes: secretion, glycosylation and
RT   lipid binding characteristics.";
RL   Mol. Biochem. Parasitol. 122:161-170(2002).
CC   -!- FUNCTION: Binds retinol and different fatty acids. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12106870}.
CC   -!- PTM: N-glycosylated. {ECO:0000269|PubMed:12106870}.
CC   -!- SIMILARITY: Belongs to the fatty-acid and retinol-binding protein
CC       (FARBP) family. {ECO:0000250|UniProtKB:Q25619, ECO:0000305}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AY050253; AAL33789.1; -; mRNA.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0005504; F:fatty acid binding; ISS:UniProtKB.
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0019841; F:retinol binding; ISS:UniProtKB.
DR   InterPro; IPR008632; Gp-FAR-1.
DR   Pfam; PF05823; Gp-FAR-1; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Glycoprotein; Lipid-binding; Retinol-binding; Secreted;
KW   Signal; Vitamin A.
FT   SIGNAL        1     16       {ECO:0000255}.
FT   CHAIN        17    178       Fatty-acid and retinol-binding protein 1.
FT                                {ECO:0000255}.
FT                                /FTId=PRO_0000008763.
FT   COILED       67     89       {ECO:0000255}.
FT   COILED      123    154       {ECO:0000255}.
FT   CARBOHYD     44     44       N-linked (GlcNAc...). {ECO:0000255}.
FT   CARBOHYD     75     75       N-linked (GlcNAc...). {ECO:0000255}.
FT   CARBOHYD    157    157       N-linked (GlcNAc...). {ECO:0000255}.
SQ   SEQUENCE   178 AA;  20611 MW;  DF1C73CDF55FE17F CRC64;
     MYHQLILMAL IGVIMANVVP FSMSNIPEEY KEFIPEEVKN FYKNLTQEDR QILRELASKH
     ATFTNEDAAL EALKNKSDKL YQKAVELRNF VKAKIDSLKP DAKTFVDEII AKVRSLRPED
     GQKLDMEKIK QAARDIIAKY EALNEETKEE LKATFPNTTK IITNEKFKRI ANSFLQKN
//
DBGET integrated database retrieval system