ID G0A0E5_METMM Unreviewed; 429 AA.
AC G0A0E5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=NAD-dependent epimerase/dehydratase {ECO:0000313|EMBL:AEG02451.1};
GN OrderedLocusNames=Metme_4098 {ECO:0000313|EMBL:AEG02451.1};
OS Methylomonas methanica (strain MC09).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomonas.
OX NCBI_TaxID=857087 {ECO:0000313|EMBL:AEG02451.1, ECO:0000313|Proteomes:UP000008888};
RN [1] {ECO:0000313|EMBL:AEG02451.1, ECO:0000313|Proteomes:UP000008888}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC09 {ECO:0000313|EMBL:AEG02451.1,
RC ECO:0000313|Proteomes:UP000008888};
RX PubMed=22123758; DOI=10.1128/JB.06267-11;
RA Boden R., Cunliffe M., Scanlan J., Moussard H., Kits K.D., Klotz M.G.,
RA Jetten M.S., Vuilleumier S., Han J., Peters L., Mikhailova N., Teshima H.,
RA Tapia R., Kyrpides N., Ivanova N., Pagani I., Cheng J.F., Goodwin L.,
RA Han C., Hauser L., Land M.L., Lapidus A., Lucas S., Pitluck S., Woyke T.,
RA Stein L., Murrell J.C.;
RT "Complete Genome Sequence of the Aerobic Marine Methanotroph Methylomonas
RT methanica MC09.";
RL J. Bacteriol. 193:7001-7002(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MC09;
RA Boden R., Cunliffe M., Scanlan J., Moussard H., Kits K.D., Klotz M.,
RA Jetten M., Vuilleumier S., Han J., Peters L., Mikhailova N., Teshima H.,
RA Tapia R., Kyrpides N., Ivanova N., Pagani I., Cheng J.-F., Goodwin L.,
RA Han C., Hauser L., Land M., Lapidus A., Lucas S., Pitluck S., Woyke T.,
RA Stein L.Y., Murrell C.;
RT "Complete genome sequence of the aerobic marine methanotroph Methylomonas
RT methanica MC09.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000008888}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC09 {ECO:0000313|Proteomes:UP000008888};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Stein L., Woyke T.;
RT "Complete sequence of Methylomonas methanica MC09.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002738; AEG02451.1; -; Genomic_DNA.
DR RefSeq; WP_013820667.1; NC_015572.1.
DR AlphaFoldDB; G0A0E5; -.
DR STRING; 857087.Metme_4098; -.
DR KEGG; mmt:Metme_4098; -.
DR eggNOG; COG0702; Bacteria.
DR HOGENOM; CLU_007383_6_5_6; -.
DR OrthoDB; 9776313at2; -.
DR Proteomes; UP000008888; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR025695; DoxX-like.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR12126:SF11; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12126; NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED; 1.
DR Pfam; PF13781; DoxX_3; 1.
DR Pfam; PF13460; NAD_binding_10; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008888};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..154
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF13460"
SQ SEQUENCE 429 AA; 47011 MW; D9F89C966AB69D14 CRC64;
MNILLTGATG FIGNAILRAL LQQGHQVKAC CRHPDSLLLD KPALTVLPID YRQAFTPQHW
LPHLTGIDAI VNCVGIIAES SDGTFDQLHR QTPIALFQAG AEIGVKKIVQ ISALGADENA
ETAYHLSKKA ADDALRRLPL DWFLLQPSIV YGGRAQSSGL FHALAALPVH LLPDGGRQLL
QPIPIDDVAA AVTCCLEPAV LGKKTLALVG PEPISYADWL QSLRRRLGKP PARRWPVSSR
FSEAVAGLGK WLGEPVLSKD NIVMLNRGNA ADPGPISELL GRPPRDMASQ LFEKPASQAE
RWHAMLYFVK PLLCLSIAFV WLWSGITSLL FYPHELSYRL LADISITGIG APLTLYGLAA
LDIVLGLTTL ARFRPRELML WQFCIVLGYS LAVAVCLPEF VFHPFGPLLK NLPFLICLVI
YRQLEGEKP
//
