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Database: UniProt
Entry: G0A3D7_METMM
LinkDB: G0A3D7_METMM
Original site: G0A3D7_METMM 
ID   G0A3D7_METMM            Unreviewed;       245 AA.
AC   G0A3D7;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   05-JUL-2017, entry version 39.
DE   RecName: Full=Flagellar brake protein YcgR {ECO:0000256|HAMAP-Rule:MF_01457};
DE   AltName: Full=Cyclic di-GMP binding protein YcgR {ECO:0000256|HAMAP-Rule:MF_01457};
GN   Name=ycgR {ECO:0000256|HAMAP-Rule:MF_01457};
GN   OrderedLocusNames=Metme_1819 {ECO:0000313|EMBL:AEG00236.1};
OS   Methylomonas methanica (strain MC09).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylomonas.
OX   NCBI_TaxID=857087 {ECO:0000313|EMBL:AEG00236.1, ECO:0000313|Proteomes:UP000008888};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MC09;
RA   Boden R., Cunliffe M., Scanlan J., Moussard H., Kits K.D., Klotz M.,
RA   Jetten M., Vuilleumier S., Han J., Peters L., Mikhailova N.,
RA   Teshima H., Tapia R., Kyrpides N., Ivanova N., Pagani I., Cheng J.-F.,
RA   Goodwin L., Han C., Hauser L., Land M., Lapidus A., Lucas S.,
RA   Pitluck S., Woyke T., Stein L.Y., Murrell C.;
RT   "Complete genome sequence of the aerobic marine methanotroph
RT   Methylomonas methanica MC09.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000008888}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC09 {ECO:0000313|Proteomes:UP000008888};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Teshima H., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Pagani I., Stein L., Woyke T.;
RT   "Complete sequence of Methylomonas methanica MC09.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a flagellar brake, regulating swimming and
CC       swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-
CC       dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing
CC       levels of c-di-GMP lead to decreased motility. {ECO:0000256|HAMAP-
CC       Rule:MF_01457}.
CC   -!- SUBUNIT: Monomer. Interacts with the flagellar basal bodies.
CC       {ECO:0000256|HAMAP-Rule:MF_01457}.
CC   -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body
CC       {ECO:0000256|HAMAP-Rule:MF_01457}.
CC   -!- SIMILARITY: Belongs to the YcgR family. {ECO:0000256|HAMAP-
CC       Rule:MF_01457}.
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DR   EMBL; CP002738; AEG00236.1; -; Genomic_DNA.
DR   RefSeq; WP_013818488.1; NC_015572.1.
DR   STRING; 857087.Metme_1819; -.
DR   EnsemblBacteria; AEG00236; AEG00236; Metme_1819.
DR   KEGG; mmt:Metme_1819; -.
DR   eggNOG; ENOG4108REP; Bacteria.
DR   eggNOG; COG5581; LUCA.
DR   OMA; RYIFRID; -.
DR   OrthoDB; POG091H0NAE; -.
DR   Proteomes; UP000008888; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0035438; F:cyclic-di-GMP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-HAMAP.
DR   GO; GO:0071945; P:regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed; IEA:UniProtKB-HAMAP.
DR   Gene3D; 2.30.110.10; -; 1.
DR   HAMAP; MF_01457; YcgR; 1.
DR   InterPro; IPR009875; PilZ_domain.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   InterPro; IPR023787; T3SS_YcgR.
DR   InterPro; IPR009926; T3SS_YcgR_N.
DR   Pfam; PF07238; PilZ; 1.
DR   Pfam; PF07317; YcgR; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum {ECO:0000256|HAMAP-Rule:MF_01457};
KW   c-di-GMP {ECO:0000256|HAMAP-Rule:MF_01457};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008888};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01457};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008888}.
FT   DOMAIN        7    111       T3SS_YcgR_N. {ECO:0000259|Pfam:PF07317}.
FT   DOMAIN      115    235       PilZ. {ECO:0000259|Pfam:PF07238}.
SQ   SEQUENCE   245 AA;  28043 MW;  CCF38CD7677B5140 CRC64;
     MATESEYIVK NAKMVFNHFN ELVTKKCLIS AHFGDRNTSF LTTIIELDPK KKLLQLDCGP
     SEAVDSQLLA SEKVLFRTEY NGIKVSFSAK NIQKIKSGGE SVFSMPIPDS IFWMQRRQYY
     RVRIPYSHNG SYCQLTFKSE QDDSVETLKF PLYDLSMTGI AFLNPDPKWA EHMQPDCQFT
     DCSLHLHNGN HAIVGFIIKN NVKVRSGTMT LQDKIGCLFQ SMPTNFETSI QRYMQEIELQ
     QKNAG
//
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