ID   G0B191_9GAMM            Unreviewed;       359 AA.
AC   G0B191;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   SubName: Full=2-hydroxypropyl-CoM lyase {ECO:0000313|EMBL:AEG10497.1};
DE            EC=4.4.1.23 {ECO:0000313|EMBL:AEG10497.1};
GN   ORFNames=Sbal175_1220 {ECO:0000313|EMBL:AEG10497.1};
OS   Shewanella baltica BA175.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=693974 {ECO:0000313|EMBL:AEG10497.1, ECO:0000313|Proteomes:UP000002249};
RN   [1] {ECO:0000313|EMBL:AEG10497.1, ECO:0000313|Proteomes:UP000002249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BA175 {ECO:0000313|EMBL:AEG10497.1,
RC   ECO:0000313|Proteomes:UP000002249};
RX   PubMed=22328742; DOI=10.1128/JB.06468-11;
RA   Caro-Quintero A., Auchtung J., Deng J., Brettar I., Hofle M., Tiedje J.M.,
RA   Konstantinidis K.T.;
RT   "Genome sequencing of five Shewanella baltica strains recovered from the
RT   oxic-anoxic interface of the Baltic Sea.";
RL   J. Bacteriol. 194:1236-1236(2012).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase
CC       family. {ECO:0000256|ARBA:ARBA00009553}.
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DR   EMBL; CP002767; AEG10497.1; -; Genomic_DNA.
DR   RefSeq; WP_006082624.1; NC_017571.1.
DR   AlphaFoldDB; G0B191; -.
DR   KEGG; sbb:Sbal175_1220; -.
DR   HOGENOM; CLU_040013_3_0_6; -.
DR   Proteomes; UP000002249; Chromosome.
DR   GO; GO:0050555; F:2-hydroxypropyl-CoM lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR   CDD; cd03311; CIMS_C_terminal_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR002629; Met_Synth_C/arc.
DR   InterPro; IPR016456; Met_Synthase_cat.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   PANTHER; PTHR30519; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR30519:SF0; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR   Pfam; PF01717; Meth_synt_2; 1.
DR   PIRSF; PIRSF005632; Met_synth_catalytic_prd; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:AEG10497.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          20..344
FT                   /note="Cobalamin-independent methionine synthase MetE C-
FT                   terminal/archaeal"
FT                   /evidence="ECO:0000259|Pfam:PF01717"
SQ   SEQUENCE   359 AA;  40391 MW;  79A48FDE5A56D7BF CRC64;
     MTTLLNKTSL NKTLLNQTLL PTSTAGSLPK PVWLAEPQTL WSPWKLQGEE LIAGKHDALR
     LSLQDQLHAG IDIVSDGEQT RQHFVTTFIE HLNGVDFSKR KTVKIRDRYD ASVPTVVGPV
     SRQKSVFVED AKFLRKQTTQ PIKWALPGPM TMIDTLYDDH YKSREKLAWE FAKILNEEAK
     ELEAAGVDII QFDEPAFNVF FDEVNDWGIA CLERAIEGLK CETAVHICYG YGIKANTDWK
     KTLGSEWRQY EEAFPKLQKS NIDIISLECH NSHVPMELLE LIRGKKVMVG AIDVATDTIE
     TAEEVADTLR KALKFVDADK LYPCTNCGMT PLSHQVARGK LNALSAGAEI VRKELLALR
//