ID G0EX48_CUPNN Unreviewed; 333 AA.
AC G0EX48;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cysteine synthase CysK {ECO:0000313|EMBL:AEI77221.1};
DE EC=2.5.1.47 {ECO:0000313|EMBL:AEI77221.1};
GN Name=cysK {ECO:0000313|EMBL:AEI77221.1};
GN OrderedLocusNames=CNE_1c18810 {ECO:0000313|EMBL:AEI77221.1};
OS Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453
OS / N-1) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1042878 {ECO:0000313|EMBL:AEI77221.1, ECO:0000313|Proteomes:UP000006798};
RN [1] {ECO:0000313|EMBL:AEI77221.1, ECO:0000313|Proteomes:UP000006798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1
RC {ECO:0000313|Proteomes:UP000006798};
RX PubMed=21742890; DOI=10.1128/JB.05660-11;
RA Poehlein A., Kusian B., Friedrich B., Daniel R., Bowien B.;
RT "Complete genome sequence of the type strain Cupriavidus necator N-1.";
RL J. Bacteriol. 193:5017-5017(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP002877; AEI77221.1; -; Genomic_DNA.
DR RefSeq; WP_013956851.1; NC_015726.1.
DR AlphaFoldDB; G0EX48; -.
DR KEGG; cnc:CNE_1c18810; -.
DR HOGENOM; CLU_021018_1_0_4; -.
DR Proteomes; UP000006798; Chromosome 1.
DR GO; GO:0004124; F:cysteine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR001216; P-phosphate_BS.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF211; PALP DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS00901; CYS_SYNTHASE; 1.
PE 4: Predicted;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transferase {ECO:0000313|EMBL:AEI77221.1}.
FT DOMAIN 10..301
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 333 AA; 35585 MW; C21D84BBB815FC6B CRC64;
MEVRDGFAGT IGHTPLIRLA GLSAETGCDI YGKAEFLNPG GSVKDRAALY IIRDAERRGL
LTPGGTVIEG TAGNTGIGLA HLCAARGYRC IVVIPDTQSP EKMERLRMLG AEVRAVPAKP
YADPDNYQKI AGRLADQTDN AIWANQFDNL ANRQAHYETT GPEIWHATGG HIDAFTCSTG
TGGSLAGIAR CLKEHKPGVR IVLADPHGSG LYHFVKHREV KVEGSSITEG IGSSRVTANL
QDTPIDDAVR IDDQTCVDMV YRLLREEGLF VGGSSGINVG AAVALAREMG PGHTIVTLLC
DRGDLYMARL FNEAWLEGKG LQPIPFRRAG PAG
//
