ID   G0HWH8_HALHT            Unreviewed;       922 AA.
AC   G0HWH8;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   Name=boa6 {ECO:0000313|EMBL:AEM57792.1};
GN   OrderedLocusNames=HAH_2203 {ECO:0000313|EMBL:AEM57792.1};
OS   Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182
OS   / NCIMB 2187 / VKM B-1755).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=634497 {ECO:0000313|EMBL:AEM57792.1, ECO:0000313|Proteomes:UP000005629};
RN   [1] {ECO:0000313|EMBL:AEM57792.1, ECO:0000313|Proteomes:UP000005629}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 /
RC   VKM B-1755 {ECO:0000313|Proteomes:UP000005629};
RX   PubMed=21994921; DOI=10.1128/JB.05953-11;
RA   Liu H., Wu Z., Li M., Zhang F., Zheng H., Han J., Liu J., Zhou J., Wang S.,
RA   Xiang H.;
RT   "Complete genome sequence of Haloarcula hispanica, a model haloarchaeon for
RT   studying genetics, metabolism, and virus-host interaction.";
RL   J. Bacteriol. 193:6086-6087(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; CP002921; AEM57792.1; -; Genomic_DNA.
DR   RefSeq; WP_014040920.1; NC_015948.1.
DR   AlphaFoldDB; G0HWH8; -.
DR   STRING; 634497.HAH_2203; -.
DR   GeneID; 23805862; -.
DR   KEGG; hhi:HAH_2203; -.
DR   eggNOG; arCOG02276; Archaea.
DR   eggNOG; arCOG02352; Archaea.
DR   eggNOG; arCOG02388; Archaea.
DR   HOGENOM; CLU_010057_3_0_2; -.
DR   OrthoDB; 234125at2157; -.
DR   Proteomes; UP000005629; Chromosome I.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR007050; HTH_bacterioopsin.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR   Pfam; PF15915; BAT; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF04967; HTH_10; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50113; PAC; 2.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          270..340
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          345..397
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          398..470
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          474..527
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
SQ   SEQUENCE   922 AA;  100640 MW;  ADDADCD4FAC94C24 CRC64;
     MIGNGLDDVA FAGARQTGAA SRDIEVVYLD SDATAREQIH EVLADHSAEM TVTSVATTDA
     ALEAAASTAV SCLVLDPTGL GDIPAPLVSN DRYPVVLYTD ATAPDSAATV FDDAETVVRK
     QGDGQPTFLA EKIVSVVSAS ADRTESALRD ALSGIESRAE ANEIAVLLAD DGTVHWSSDS
     VSTFVDRLDD TRRVEGFYDA MRTALPDTPG GRRQLQRLRD APTEPVAVRV PGSDRDQYLL
     RHGHELPDAA GGLTLVLLRD ITETARRDAR TALLDLLVEQ AQDGLYTLDE RGVIDFCNES
     FAANLGYEPD ELCGEHASTV LAPGELSKGQ ATVETLLETP EKESTTADLT FYRKDGTERE
     VSINYTLIHD EAGNYSGLIG VARDITERCN REREYQEMTE RLNLALEGAE LGVWDWNPKT
     NDVTFDERWT GMLGYTTNEL EPHYETWADL VHPDDLNRVE QALAELKSGE TDLYQSEFRM
     RTKDGDWRWI RDIGKVFEWN DDGEAIRAVG IHQDITEERK RQDAIERQRD ELATLNGVNM
     LIQDLIHALG GAATRHETAE TVCERIVESD LCELAWIGER AGADDRLVPK TVAGDNSDVL
     DDLIVSDGND QVLCATALVT GAVQTIQDCG DPSEFKQCGA AAREQGFKSA AAIPLVQGNT
     VHGVLCVYAD QPAAFGGRIA DSFAVLGKMV GYTLAAVQNR QLLSDDTTLE LTFESECSDI
     PLVSAANAYG CRIEVVESVD TEPTHLLYVS VDEGPPDAVS AHLCSQTEIL GSRVVRADDS
     SGIIELQVTE TVQSLLLDVG ARCRTVVADD GALSITVEAP PDADSRAIRD AVSDRVPDST
     LTAKQECDRT DDILDTETDP RNHLTDRQKE VLRTAFLTGY YAWPRDTNAE QLAERLSIAS
     PTLHQHLRRA QRNLIDAVFD MQ
//