ID   G0LMX4_HALWC            Unreviewed;       796 AA.
AC   G0LMX4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Endoisopeptidase/DUF4129 domain protein {ECO:0000313|EMBL:CCC41444.1};
GN   OrderedLocusNames=Hqrw_3704 {ECO:0000313|EMBL:CCC41444.1};
OS   Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloquadratum.
OX   NCBI_TaxID=768065 {ECO:0000313|EMBL:CCC41444.1, ECO:0000313|Proteomes:UP000007954};
RN   [1] {ECO:0000313|EMBL:CCC41444.1, ECO:0000313|Proteomes:UP000007954}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16854 / JCM 12705 / C23
RC   {ECO:0000313|Proteomes:UP000007954};
RX   PubMed=21701686; DOI=10.1371/journal.pone.0020968;
RA   Dyall-Smith M., Pfeiffer F., Klee K., Palm P., Gross K., Schuster S.C.,
RA   Rampp M., Oesterhelt D.;
RT   "Haloquadratum walsbyi: limited diversity in a global pond.";
RL   PLoS ONE 6:E20968-E20968(2011).
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DR   EMBL; FR746099; CCC41444.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0LMX4; -.
DR   KEGG; hwc:Hqrw_3704; -.
DR   HOGENOM; CLU_022005_0_0_2; -.
DR   OrthoDB; 18481at2157; -.
DR   Proteomes; UP000007954; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR025403; TgpA-like_C.
DR   InterPro; IPR021878; TgpA_N.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF13559; DUF4129; 1.
DR   Pfam; PF11992; TgpA_N; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        113..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        147..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        172..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        203..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          448..518
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          519..611
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          674..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        520..611
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        675..695
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   796 AA;  85529 MW;  2A5C7B6CF706A9E4 CRC64;
     MNRSYISYRI NEVSKMASRP SILAAIGIIA VTWSYVSVLA DIATVTGWRT PFLFVVVLAG
     VLGVMIGTIG RTRSAFILTI GLLLIGLITY IYTLSQAQQQ LLTTQRLLAD TAALFTGLSI
     LRFVRAGAWA IAVVPAPVFL SWALLSAGRY VLSATAGGVI LGLVILTGDA GLLTALTGVV
     GFLLTVAAAT LTQYDGDINQ LDAVIVLLAV IIVLSTSVSA VPGSGSSPLV PEKTPQTVDA
     SLTTADQRIE VLGSIDLSPQ VRFTVESSRP SYWRTGAYNR YTGDGWVRTG ETQPYQGQLS
     LPPGSSQSVQ QTIKTQQSIS ILPAAWKPIT IEGSAASQAT VTTQGGLIPQ TSLSANTEYT
     VTSRLPLWTP AQLRRAGTAY PAEIDETYRE VPADTSNRVT QRTNQIISNA SADTPYDAAI
     AVERYLESNK QYSLSVSKPD GNVAESFLFE MDAGYCVYYA STMAVMLRTQ GIPTRFVTGY
     TPGQRIDSNT HVVRGLNSHA WVEVYFPDTG WVRFDPTPAA ERQSTESARL SEARQQDTAG
     IDLNESTPTP TPGSSAMTPE NGASTDATGT TSAPTERSTT TPQGTDINNN SAGSMAQTPG
     ISARTGDPLG SSSPSVIDQF LPTVRIRRLL AVIAIGIIGM GAAMRQSHTI QCSRRLVMAQ
     SQWLQSIRQH KRRFAGIRGV SEGKSKSKSK SKSKSDPDSS VAYAYQRAMA VLAYTHRPRR
     PNETLRTYRA ALSLSADREA ALQQIEQAYE RSKYGDGVSP PTATTAITAA DFLVRTGTPV
     RRRIAQFREI KPPDDE
//