ID G0M0Y6_LACPE Unreviewed; 869 AA.
AC G0M0Y6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=ATP-dependent RecD-like DNA helicase {ECO:0000256|HAMAP-Rule:MF_01488};
DE EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_01488};
GN Name=recD2 {ECO:0000256|HAMAP-Rule:MF_01488};
GN ORFNames=LPENT_03047 {ECO:0000313|EMBL:CCC18351.1};
OS Lactiplantibacillus pentosus IG1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1042160 {ECO:0000313|EMBL:CCC18351.1};
RN [1] {ECO:0000313|EMBL:CCC18351.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IG1 {ECO:0000313|EMBL:CCC18351.1};
RA Maldonado-Barragan A., Caballero-Guerrero B., Lucena-Padros H.,
RA Ruiz-Barba J.L.;
RT "Genome Sequence of Lactobacillus pentosus IG1, a Strain Isolated from
RT Spanish-Style Green Olive Fermentations.";
RL J. Bacteriol. 193:5605-5605(2011).
CC -!- FUNCTION: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase.
CC Has no activity on blunt DNA or DNA with 3'-overhangs, requires at
CC least 10 bases of 5'-ssDNA for helicase activity. {ECO:0000256|HAMAP-
CC Rule:MF_01488}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01488};
CC -!- SIMILARITY: Belongs to the RecD family. RecD-like subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01488}.
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DR EMBL; FR874854; CCC18351.1; -; Genomic_DNA.
DR AlphaFoldDB; G0M0Y6; -.
DR GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd17933; DEXSc_RecD-like; 1.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 1.10.10.2220; -; 1.
DR Gene3D; 2.30.30.940; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01488; RecD_like; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR006345; DNA_helicase_RecD-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029493; RecD-like_HHH.
DR InterPro; IPR041451; RecD-like_SH13.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; TIGR01448; recD_rel; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF14490; HHH_4; 1.
DR Pfam; PF18335; SH3_13; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01488}; DNA-binding {ECO:0000256|HAMAP-Rule:MF_01488};
KW Helicase {ECO:0000256|HAMAP-Rule:MF_01488};
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01488, ECO:0000313|EMBL:CCC18351.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01488}.
FT DOMAIN 361..518
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 766..841
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..841
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 372..376
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01488"
SQ SEQUENCE 869 AA; 95198 MW; D5657414636A03AB CRC64;
MTDEQANLFS DDVGRNPVSH FVVGKVAATF FSSSDSFYKV LLVKVTEQNI DWSEDEIVVT
GNFADIQEET TYRFTGRTVT HPKYGVQFQA DNYQNETPTT RSGLIAYLSG NDFPGLGKRT
AERIVDTLGE DAIDKILADP KVLKPIGLRA GVQATLVDTL TVNNGLEQTI IGLNAYGFGS
RLAAAIYARY QGDTLARIQE NPYCLVEDIK GVGFKKADQI AAQLNIDPQA DERLKAALLT
EIDELCVANG DTYTTAKPLL NQTLQLLENA RHVRIDPDKL ADQLVVLAKE NKIVGDENRI
YLRGLYEAEW RVAEQLKRLL DEEDEHPLTD KAVESAIQHV SRASNITYDA SQTAALKAAI
TSHVFLLTGG PGTGKTTIIR GLVALYAELH DVVLDVNQYK DEPFPISLAA PTGRAAKRMA
ETTGLPASTI HRLLGLTGRE DGPEEPSKEL QGGILIIDEM SMVDTVLFQQ LLTSIPSEMQ
VIFVGDKDQL PSVGAGQVFH DLLQFSELPQ IELTTIYRQG NDSSIIPLAH AIKDGQLPAD
FTVNQPDRSF ISCNAYQVNH IIEQVVGKAK AKGFSADDVQ ILAPMYRGTA GIDQLNTTVQ
NIFNPLKSAR QKHLTYNGQD FRVGDKVLHL VNSPEDNVFN GDIGRIVGID LAGDPHNESK
KDQITIAFDQ NEVTYQRSDW NRLTLAYSMS IHKSQGSQFK MVILPMVPQF SRMLQRNLLY
TAVTRAEQML ILLGDIQSFE RSVTNESVNR QTTLTKRLRQ VWGIETSDEA DEPEASAEPA
TDVEAAAGDS ETTTEGEPTQ AKSENDDDVT SAQSVETAAD DGESGASTAA QPTQGPTVLT
PTLVLSRQID PMIGMAGIKP TDFMPQATN
//
