ID G0M7H7_CAEBE Unreviewed; 1631 AA.
AC G0M7H7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0000259|PROSITE:PS50067};
GN ORFNames=CAEBREN_29246 {ECO:0000313|EMBL:EGT29944.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; GL379786; EGT29944.1; -; Genomic_DNA.
DR STRING; 135651.G0M7H7; -.
DR EnsemblMetazoa; CBN29246.1; CBN29246.1; WBGene00191211.
DR eggNOG; KOG0241; Eukaryota.
DR HOGENOM; CLU_001485_29_2_1; -.
DR InParanoid; G0M7H7; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0030424; C:axon; IEA:EnsemblMetazoa.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:EnsemblMetazoa.
DR GO; GO:0043025; C:neuronal cell body; IEA:EnsemblMetazoa.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT DOMAIN 9..347
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 478..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1358..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1452..1476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 362..406
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 99..106
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1631 AA; 183224 MW; BD321FD0B02D0AF5 CRC64;
MTVPDEESAV KVAIRVRPFN KRELDLKTKS VVRIQKEQCV LNHPVEEKNS KTFTFDHSFC
STDPRSHDFA SQETVCYHLG SGVVENAFSG YNACIFAYGQ TGSGKSYTMM GTPDQPGIIP
RVCNDIFTRI HETTNSTLSF KVEVSYMEIY NERVRDLLDP KKSSKALKVR EHKILGPMVD
GLSILAVNSF EQISNLLEEG NKSRTVAATN MNAESSRSHA VFSLIVTQTL HDLENGFSGE
KVAKISLVDL AGSERAGKTG AVGKRLEEGG NINKSLTTLG MVISALAERN AKKDKFIPYR
DSVLTWLLKD SLGGNSKTVM IATLSPAADN YEETLSTLRY ADRAKKIVNH AIINEDPNAR
VIRELREEVE TLRMQITQTK KEHAETEELR ERLAESERLV AQMNKSWEER LKETDTLNKE
RQKDLAEIGI SIESSGIKVE KDRFYLVNMN ADPSLNELLV YYINGSAIIG NSEELETSRD
SGLSMASNES KKDDEKERTS IVLRGLGIMR RHAKLTVEEY GGRMRLFVAP MSSECRICVN
GKQITERTLL RNGNRMLVGM NHFFKVNCPK VMDMEQSIME DSTMFDYNDA WHEVNDANPI
SSAVDQYMES VTLKHQEDKK AALEQQYEAF EKYIQSLTAG GFTPSTPMTP GFGLPTPITT
PTGLPPFPFP TNPKQSVKSK FFYWAQRKEE MFAESLKRLK ADVIHANALV REANMISKEL
NKKPKRQTTY DVTLQIPASN LRPIKIKAGQ FVCEPVIVVR REGMSGSQFW TVSQLESRLV
DMRDTYNDML NGFSRLGIHI IIPENILFSI YRASESLNGT PNASPMKAAG IPLNECSSLV
IDPFFESQEH HNLVGVANVF LEVLFHDLRL DYQVPIISQQ GEVAGRLHVQ IFRVVTQEEI
DSQANNGPES LLGKTITCRV RIKRASGLPE KLSNFVFCQY SFFNISELLV VAPANETANH
STCATTVIFE HQRDFNVTVT EEFMEYVRDD ALSIEVWGHR ICGHPEERVL DTDEKCKSLQ
NRWMEVTRRL EMWAEVRELN ENGEWTSVEV RNVEDVATGG IYQLKQGQQR RLVVGVNVAA
PDGLPISIDS ITSVSIGAIM TVKPNNSKSI DSYQEEDLDK IRKQWSHALK SRQYYLQHQL
DTLSAKSGKS EAELDREHSL MGQWVALTEE RTAVECPAPN SCIPGAPCDW IAPEGVERHI
PVLFLDLNSD DMTGELTSDE NVPRVAGLHS MLPLEPEGNL LMLPIHKYDD KDHVATCSWD
SSVHDSPALN VPTNNNDRVY AIVKIMVRLS HPCPMHIVLR KRICLQIYKK PSLTEKFFKK
MLGTETIHRT SLYYDVVAHI PKSSQDMEDR SSLAMMAAKD TSQDEQGGGS SRSSTSSTES
QYQQQTLNYI EAYTKSIQAV ESMLKLDRLR QEVAITNMLT KKERLQRIQN FGLPMHSLRM
NRAVSLPNAI SSAGQIPGPD KRSDTPMSIS SSNSMARPTS LNLKPLCIGK CRFCLLPCPR
DELQFFISSF LLHDLCTLRF LHLFQLLNQF SVTSIISPYN DKLTGIIEES NSLKIETIPT
RSSTVPETMC FAAAKKLSPT EDVKNGNEES SASRFANGTS MGVNLCLPLE NNNQFASKKL
QNGDLVDLKI N
//
