ID   G0MCL5_CAEBE            Unreviewed;       781 AA.
AC   G0MCL5;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=CBN-CPT-1 protein {ECO:0000313|EMBL:EGT49728.1};
GN   Name=Cbn-cpt-1 {ECO:0000313|EMBL:EGT49728.1};
GN   ORFNames=CAEBREN_21409 {ECO:0000313|EMBL:EGT49728.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
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DR   EMBL; GL379790; EGT49728.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0MCL5; -.
DR   STRING; 135651.G0MCL5; -.
DR   EnsemblMetazoa; CBN21409.1; CBN21409.1; WBGene00160134.
DR   eggNOG; KOG3716; Eukaryota.
DR   HOGENOM; CLU_013513_2_1_1; -.
DR   InParanoid; G0MCL5; -.
DR   OMA; NTEHSWG; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004095; F:carnitine O-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 6.10.250.1760; -; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR   InterPro; IPR000542; Carn_acyl_trans.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR039551; Cho/carn_acyl_trans.
DR   InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR   InterPro; IPR032476; CPT_N.
DR   PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR22589:SF31; CARNITINE O-PALMITOYLTRANSFERASE; 1.
DR   Pfam; PF00755; Carn_acyltransf; 1.
DR   Pfam; PF16484; CPT_N; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000256|RuleBase:RU003801};
KW   Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        50..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..47
FT                   /note="Carnitine O-palmitoyltransferase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16484"
FT   DOMAIN          175..759
FT                   /note="Choline/carnitine acyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00755"
FT   ACT_SITE        474
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ   SEQUENCE   781 AA;  89546 MW;  92D9F0BD773237B8 CRC64;
     MAEARSAAAL SFAVTHDGVS VSYDQELLRD IWHGISRSYK RRTGRFRNDF MNGMFPANSW
     TLGLVVGAVA VFSVLKHDLS FGIFPFIQNY IVHYIFGDGY LGQSISIAVA GALLWLIFVQ
     LLRLSIKTLL EYKGWMYESP GKPVSKATKL WLGVLHIISK AGPMLHSFQG ALPRLPLPQL
     DDTVRKHLLS MKPILSDEEY QELEFLSERF RKGVGRRLQR YLTLKSWFSS NYVTDWWEEF
     VYMRQRSPIM INSNYYGFDT LNEHPTTNQA SRAANLTYTS LQFRRMVDRQ EVSPFSISPR
     TKVPFCTMQY ERLFNTCRVP GEEVDRLLHW DDAKHVAVYS KGVWFKLIVH NGKRLLDACE
     LQHQYDSILA HTYEPSEGEK HLASLTAGER ADWAKTRRAH FRSGINKTSL NDIERAAFVV
     ILDDEETHYD PEDPSKLDHW AHNLLHGKAY DRWFDKSFNL IISKNGHVGI NTEHSWGDAA
     VMAHFTEWSL LQDIIFIGYD ENGRCKGTPK EKLTPERLKW DIPTPALDQI RKSMEVANAL
     IADVEMSLLV WTDYGKGFAK KLKVSPDAFL QMTLQYTYFK NQGKFSLTYE ASMTRLFREG
     RTETVRSCTV QSSEFVRSML DKSKTPQDRL QLLRKACDKH QELYRDAMCG QGVDRHLFAL
     YVIKRYLEEE SPFFDKIFPP TYLLSTSQTP MNQCEADAKG LSDEVRLRLI TAGGGFGPVA
     DRGYGVSYIV AGENTLSFHI SSKRSAENTS SREFREELKR SLADMKKLAD ALETAPKKAV
     Q
//