ID G0MH26_CAEBE Unreviewed; 2492 AA.
AC G0MH26;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=CBN-HIM-4 protein {ECO:0000313|EMBL:EGT58071.1};
GN Name=Cbn-him-4 {ECO:0000313|EMBL:EGT58071.1};
GN ORFNames=CAEBREN_12159 {ECO:0000313|EMBL:EGT58071.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GL379794; EGT58071.1; -; Genomic_DNA.
DR STRING; 135651.G0MH26; -.
DR EnsemblMetazoa; CBN12159.1; CBN12159.1; WBGene00150884.
DR eggNOG; KOG4475; Eukaryota.
DR HOGENOM; CLU_228585_0_0_1; -.
DR InParanoid; G0MH26; -.
DR OMA; DQSEITW; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00096; Ig; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 20.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12231:SF253; NEURAL CELL ADHESION MOLECULE; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF07679; I-set; 17.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00409; IG; 19.
DR SMART; SM00408; IGc2; 20.
DR SMART; SM00406; IGv; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 21.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50835; IG_LIKE; 20.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 60..146
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 151..236
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 241..326
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 331..411
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 414..499
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 504..590
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 595..678
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 687..776
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 780..875
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1057..1146
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1150..1236
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1243..1334
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1337..1423
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1428..1514
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1519..1605
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1610..1697
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1702..1787
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1862..1945
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1966..2038
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2042..2127
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2290..2327
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 958..984
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2137..2218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2143..2157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2167..2200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 2294..2304
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 2492 AA; 273359 MW; 2FBF1D990793BB87 CRC64;
MEMYDGKRLN ESYEANISED GNKLFIQSLE TDAAGRYTCI AENKAGRSEK DMIVEVQVPP
RMREYTSNIE VQEGDPLALE CPLEDTTGTT VTWYNNNNGP LFAASQQSID HKQFYVLHAK
VATETDTFYC VAQNEAGSTR ADFQVVVHTP PKIAGEAFST TEAVSNTTLT LNCLAEGVPP
PKISWHLDGT PVLGTPGVRQ TEHSLIIENI GMRQEGRYTC RAENVVGTAE QDTYVEILVP
PRVVMASETM RVVEGRQATI RCEIFGDPEP VVVWMKDGQP YRSDLLHFSS TLVYLHLREA
TQQDSGTYTC IGTNKAGESR TTTKVEVLVI PRIEDTERII QGKEGNTVQI HCPASGIPPP
SIVWKKGGVD LGQYEPTLVI KNASRSNEGK YSCYASNEAG TAVADFHLDV NTKPTFGSHK
TTFNVITGES AKIECKVDGH PKPTITWLKG GRPLAMENVI LSPRGDTLMI LKTDRHDSGL
YTCVASNAYG ENEQDFKVNV FTKPYIEQSI DQTPKGVTGA TIDLDCPVLG NPPPTVVWKQ
GDATITEDGV HYILKNTFLQ IKDVTVEDAG QFSCIATNEA GELVTNYNVD VIGKPKFDRK
ETTIYEVIEG ENIVMDCGVT TSPLPEITWY RGDKPIYLEG HYSISNDGSQ LNINKAQLSD
GGKYVCRASN EAGSADIDVL LRILIPPRID KSNIIGNPLA IVARNIYLEC PVSGIPQPHV
LWTKDGVLVD MTDSRIILAQ NNETFGIEGV KVSDQGRYTC TASNRGGKAA HDFSLDVLSP
PAFDVDGTTP TIKRQGDTIT LTCPIKTAED VADQVGDVSW TKDSRALDGD DTDNIHISDD
GRKLTIAHAT MENAGMYTCI ALNRAGEASL EFKVEILCTS LATPKCRELE NNYIARNMPH
AVTQTRESQS DAAYREHMRR YEEYLKKYEE GLQRQRDESI RRQNAYWEMR HKKESVKIVT
TTSSTTTTTT TPSPTTTTVR TSTSPVPHLP WVYNPQYGHP SGASGVMKVK ATVQHPTRQF
RTKRVKPVLR CFFYDPFRHV FLREKSSEIL PPSTKAPPII DTTRNDIQPQ VTINQPTILR
CPVTGHPFPA IKWLKNGEEV DNDENIRIVD QGQTLQILLT DPAHAGKWSC VAENDAGVKE
LEMNLDVLTP PVVTVHSENP IKAIGETITL LCNATGNPPP QIKWTKSGNM VFDAPDGARL
SLKNARLDIP RLKKTDVGDY TCQAMNSAGT AEASISVDVL VPPEITRDGI DMSPRLPAAQ
SLTLQCLAQG KPPPKLKWTV NGTEISESTP GITIGTDATF IQINNVSLID QGVYICHAEN
VAGTDDLMYN VDVVQAPIIS NGGTKQVIEG ELAVIECLVE GHPAPQVSWL RNGNRVETGV
QGVRYVTDGR QLTIIEARSL DSGIYLCSAT NEAGSAQQAY TLEVLVSPKI VSTAPETLTP
SSNSKFSLPC AVRGYPDPVI SWTANGKDIE DGAPGYTITA DGTLVVEKAE QRISSFECTA
KNDAGADTLE YKVQTIIAPK ISSSGIRYLN GSEGEETQIV CEIEADQSEI TWTKNGSPLL
PSNNLVFAEE KKQIIITSTR LTDQGEYSCT AANKAGNATQ ITQLTVGVAP KILERPRTQV
VHKGDQVTLW CEASGVPHPT ITWYKDEELL TNTGVDKTAT TRKKSVIFSS ITPSQAGVYT
CKAENWVGTV EEDVDLIVMI APEVVPERMN VSTNPRQTVF LSCNATGIPE PYISWMRDSN
VAIQSNEKYQ ILGTTLAIRN VLPEDDGFYH CIAKSDAGQK IATRKLIVNK PSDRPAPIWV
ECDEKGKPKK TEYMIDRGDT PDDNPTLLPW KDIEDSSLND SIAYRCMPGP RSSRTVLLHA
APQFIVKPKN TTAAVGAVVE LRCSAAGPPT PVITWAKDGK LIPSNKTEIA YSYLSVELRS
TEDSGEYTCM AQNSVGTSTV SATITVDNVI LPTPKPAFVK KNVAIITCYE KNLAYSRGVT
WEYNGVPMPK NLAGIHFMNN GSLVILDTSN LKEGDLSLYT CKVRNRRRYS IPHMKSVFEE
VPSVKTLDNV EVNNGDSIVL DCDVNSDPLT TNVVWTKNDQ KMLDDDAIYV LPNNSLVLLS
VEKYDEGVYK CVASNSMGIA FDDTKLSVYD GDASPLTGFE GSGSEIVESS NVGVPTRREA
QSEEEREAMA QSTATAPTDA PETTQETLLT TTSATDVSIS DPATEAPKDD FYDGSAYDPS
PTTHDLLIER QPDLHVQSSV IDTPDCFGTI NEYGDCIERN GTSHRLKILT GENRCPEGYT
FNPRTNICED IDECEFHLPC DYECINTEGS YECRCPPGYE LAEDGCYDIN ECETEKCEDG
LSCFNQLGGY ECIEDPCPAN YTLVEARYCE PECGNCTVAP IQVHMLAIPS GLPISHIATL
TAYDKNGKVL NDTTYAISEK NAPMKRGRMS SGPFSIREVK NGHAQVWTNR VLAAGDHREV
HVRAHSDHAT NDLHAPKETN FLILINVGQY PF
//
