ID   G0MUE0_CAEBE            Unreviewed;       689 AA.
AC   G0MUE0;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=Methyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CAEBREN_13966 {ECO:0000313|EMBL:EGT44233.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL379812; EGT44233.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0MUE0; -.
DR   STRING; 135651.G0MUE0; -.
DR   EnsemblMetazoa; CBN13966.1; CBN13966.1; WBGene00152691.
DR   eggNOG; KOG1269; Eukaryota.
DR   HOGENOM; CLU_399697_0_0_1; -.
DR   InParanoid; G0MUE0; -.
DR   OMA; SQFIAFD; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   CDD; cd02440; AdoMet_MTases; 2.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR048711; Rv2258c-like_HTH.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45581:SF3; METHYLTRANFER_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45581; PROTEIN CBG10435; 1.
DR   Pfam; PF21320; HTH_65; 2.
DR   Pfam; PF13847; Methyltransf_31; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT   DOMAIN          18..83
FT                   /note="S-adenosylmethionine-dependent methyltransferase
FT                   Rv2258c-like winged HTH"
FT                   /evidence="ECO:0000259|Pfam:PF21320"
FT   DOMAIN          169..283
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13847"
FT   DOMAIN          349..416
FT                   /note="S-adenosylmethionine-dependent methyltransferase
FT                   Rv2258c-like winged HTH"
FT                   /evidence="ECO:0000259|Pfam:PF21320"
FT   DOMAIN          500..614
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13847"
SQ   SEQUENCE   689 AA;  76664 MW;  184C140F88C6DB6D CRC64;
     MTLMKDKLFN LAVSNVVSNA ISVGLRLDLF KKLAEISSQE NPVLPEQLAE AAGCKERYVR
     EWMNCMACGE IIEVNEEEKF WIKKENVKDL TTSGFSTVMI ESTPTMLEPL DKLVECFKAT
     GPYGLEYSQF SKFQDFMENL SQALHEKYII ADMIPAIGYG VAEKLEAGGI RVLDVGCGIG
     FHSTLLAERY PKTQFVGLDI GSDAIKKAKT RRMKSGEPFK NLEFIECDAG KMPESWTNSF
     DLVLIFDACH DQCRPDLCIR EVQRCLKLRG VFAIVEIDSS SNVHTDKSTM GPLAALLYGR
     SMLHCLPVGS NSSDAFCLGS MWGRKRAVDL LNRCGFPEVK NLAVSQVVSN AISVGIRLNL
     FKKLADISSE KNPVLPEQLA EAAGCKERYV REWLNCMACG EIVEVNEKEQ FWIKEENVKD
     LTTNGPETVY IASTPTQLEP LDELLKCFKK EGPYGLNYSQ FSKFQDFMET LSQTLHEKHV
     VPDMIPAIGY GVAEKLEAGG IRVLDVGCGN GFHSTLLAER YPKTHFIGLD IGSDAIKKAK
     ARRMKSGAPF NNLDFIECAA GKMPDFWTDS FDLVLIFDAC HDQCRPDLCI REVQRVLKPK
     GVFAIVEINS SSNVHTDKST MGPLAALLYG RSMMHCLPVG SNSPDALCLG SMWGRKQAVD
     LLNRCGFPDV KVVDTPYFPI NVMYCAQKN
//