ID G0MY06_CAEBE Unreviewed; 371 AA.
AC G0MY06;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=CBN-DBL-1 protein {ECO:0000313|EMBL:EGT47202.1};
GN Name=Cbn-dbl-1 {ECO:0000313|EMBL:EGT47202.1};
GN ORFNames=CAEBREN_17082 {ECO:0000313|EMBL:EGT47202.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; GL379819; EGT47202.1; -; Genomic_DNA.
DR AlphaFoldDB; G0MY06; -.
DR STRING; 135651.G0MY06; -.
DR EnsemblMetazoa; CBN17082.1; CBN17082.1; WBGene00155807.
DR eggNOG; KOG3900; Eukaryota.
DR HOGENOM; CLU_020515_3_0_1; -.
DR InParanoid; G0MY06; -.
DR OMA; ICARHNE; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13761; TGF_beta_BMP5_like; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF263; PROTEIN DECAPENTAPLEGIC; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 239..371
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 237..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 371 AA; 42538 MW; 22A3A1FF76CFCE05 CRC64;
MNDSVRTTTT ISSTKSLVLR FQLSAILHIL LLSFTPFAMS ATSDQQMNRA ESHHALRRGM
LRKLGLEHVP VQTGPSIDVP QHMWDIYDDE NDVDWVRHYY PKEIVEDNDG FMLSYNLSLA
ARNAHNEEVT KAILKLRLRH NNKARRSGNF TIYFFEDDQN NERFQIESRS VDNLTEWIDF
DVTTAFSRRT DRISFFVELP EGVEIEETQS SSLSSLPYAK ARSAPLIVFS DLSEPSSVRR
KRSAQTGNSE RKNRKKGRKH QINEAENNLC RRTDLYVDFD DLGWQDWIMA PKGYDAYQCQ
GSCPNPMPAQ LNATNHAIIQ SLLHSIKPDE VPPPCCVPTE TSPLSILYMD VDKVIVIREY
ADMRVDSCGC R
//
