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Database: UniProt
Entry: G0MY32_CAEBE
LinkDB: G0MY32_CAEBE
Original site: G0MY32_CAEBE 
ID   G0MY32_CAEBE            Unreviewed;      5370 AA.
AC   G0MY32;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   07-JUN-2017, entry version 38.
DE   SubName: Full=CBN-UNC-68 protein {ECO:0000313|EMBL:EGT47004.1};
GN   Name=Cbn-unc-68 {ECO:0000313|EMBL:EGT47004.1};
GN   ORFNames=CAEBREN_24368 {ECO:0000313|EMBL:EGT47004.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL379819; EGT47004.1; -; Genomic_DNA.
DR   STRING; 135651.CBN24368; -.
DR   EnsemblMetazoa; CBN24368; CBN24368; WBGene00163093.
DR   eggNOG; KOG2243; Eukaryota.
DR   eggNOG; ENOG410YCNW; LUCA.
DR   InParanoid; G0MY32; -.
DR   OrthoDB; EOG091G00T0; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0031674; C:I band; IEA:EnsemblMetazoa.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016529; C:sarcoplasmic reticulum; IEA:EnsemblMetazoa.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   GO; GO:0040011; P:locomotion; IEA:EnsemblMetazoa.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; IEA:EnsemblMetazoa.
DR   GO; GO:0033365; P:protein localization to organelle; IEA:EnsemblMetazoa.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008068};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4734   4757       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4921   4938       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4984   5006       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   5122   5144       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   5164   5189       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   5249   5268       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      117    171       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      178    222       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      231    286       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      292    349       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      357    415       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      595    816       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1045   1227       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1555   1769       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4479   4514       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4517   4549       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4492   4503       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    4527   4538       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   5370 AA;  610849 MW;  E97CE4239803B97B CRC64;
     MDFDFTDISD EDHNYVTKGD IVCLSCVASH NRDGVLGSER VCLCTEGFGN RMCTLENVSD
     KDIPPDIAMC MLYIDNALSM RALQEMMSAD SDHVSIYVVE IKKTKLIQKS ASGAGGHKTL
     LYGHAVQLKH VQSEMYLACL SSCSSNDKLA FDVGVQETNE GEACWWTIHP ASKQRSEGEK
     VRVGDDVILV SVATERYLHM AYSKGYMVIA SFHQTLWNIQ SVSSGSMRTR NMGFLFGNDV
     LRLFHGNDEC LTIPENWSEH PQHNMVIYEG GAAVTQARSL WRVELVRMKW HGALVGWEQV
     FRIKHITSGR YLGVLDNAVQ LYHKEKADFE LTAFVMCQNK DPKKQMLDEK EEEGMGNATI
     RYGETNAFIQ HVKTQLWLSY QTSEVTKKGL GKVEEKKAVA LKDGHMDDCY TFFMALEEES
     KSARVIRKCS SVLNKFLKGI DALQLEGNKS ADWTRVDLNE VLKLMEDLIE YFAQPNEEQD
     FEEKQNHLRA LRSRQDLFQE EGVLNMILDT IDKFSQMEAL PDFADLIGED THITWEQIST
     YLYLLVAAMI KGNHYNCAQF ASAQRLDWLF GRLSNPQSAE GILDVLYCVL TESPEALNMI
     NEGHIRSVIS LLEKVGRDPK VLDVLSSLCE GNGMAVRSSQ NLITQYLLPG KDLLLQTSMR
     DHVSSMMPNV MLGVVEGSAL FRKWYFEAEV EHIETMTKQT PYLRIGWANS VGFKPFPGSG
     DKWGCNGVGD DFYSYGFDGK SMFFGGKSRI VGHKLLEKGD VVGCSIDLTV PEIKFSVNGT
     YLSGVFKKFN IDGYFFPVMS LSAKVSCRFI LGGNQGRLRY GPPPGFSAVV EAVNGELGIT
     DCLSFGDLGK NIFCGPQTIF NNLEPFIPTP IDVSTTQLTH HAMEMHQKYA ENLHELWAMR
     KIELGWSYGE NRSETSRKHP CLTRFELLPE TEKKYNIMLA LTTMKTIEAL GYHLITDDPP
     CRLRAVRLQQ NFQQSNGYKP GPLDTHEIQL PAELQPLTEA LARNTHNVWA KEKIKRGWTF
     GLSEHVDATQ KRSPHLVPYE QVDERIKQAN RESAAENIRA LQLFGIFLEP PAHEHDEVAE
     KELRARKDNT RTYRAEATYA VNGGKWYFEF EILTAGYMKI GWMDVGSTPE IQLGADDRSY
     AFDGYLGRKW HQGAETYGKE WKIGDVVGCF LDLNDRTISF SLNGELLLDP SGSEMAFDNV
     VCGDGLVPAM TLGSGQRGRL NFGQQSNSLK YFTTCGLQEG YEPFCVNMYR TMPMWFAKQL
     PRFEDISALK SGSLLEVSRI PATGTSPPCL KILQKVTISE GGPSEKAKME YIRLSLPVKC
     NDTFVKNKDK DAIRRQLQDY KPRSQSVVSQ IRAPGIPKEF EENKEKKGFL RSMLGSKDSH
     ESDDDRRSRT TSKQPSIEGD EPPAVSQRRR VLTLMNFGMY SFDESILTWL HVNEEDNHKW
     QDVLRRSLLE LPHEERQIAE DHMRDMSDRH AEKPKKGGIL SRLRDSSNTR KKDSDRRKDK
     EAALRQMKSN SRSFDAGSLD TSTLPTGQKD VLEEESEEQD PIWVLQDQFH DEDTVSASSE
     MPLSGPGRQL TIKRGSIKKN KKGKKTEIAM EKVNMEKKGS IIPMEAQLDV LQEGDAHALV
     ALKDKVDEYY YGLRIFPGQD PSQVWVGWVT TQYHYYNLNF NGSQGVRKCR FSEADHHGTT
     VDSVQSQNCY MVNVSELLAT TQDVQNTKVL GTLIGCIIDT SIGELSFQVG TTDTGIKFKL
     EPGAMLFPAV FVTPTAAELV QFELGRIKYT FPLSAAMFKS CEKSLVPFCP PRLSVEQIEP
     VYWARVPNET LRTTALKLSE VRGWSVLCND PVRIMSVYIP EKDQSLDILE MIEMPDMLEF
     HRQTLNLYCK LASHGNHKVA HTLCQHIDED QIMYAIKSHY LSGPMRQGFH DLLIGLHLMS
     HTAARNSMAK EYVIPLVPQL QIKNVLDPDS ESRYPQITGQ SVSMLSQMAS EPVKKHVSRE
     DEMKLLPPSV DFDALKKHVM ESLQSATHHA VMNCRDLIGG DNTNHFEPLF KLFDQLLVIG
     LINDEELEFL LRLIHPQAFD ETYENGTTQK GLTQLELAEP VKLQLVSILD HLCDIQLRYR
     IESLVAFTEG FVGELQSDQC KRYMEIKQTD MPPAEAAKKT KEFRCPPKEQ MFRLLMCKMK
     EEKDPELMEE DADVDQCPMA ESLQQQLRDF CELLVGKIGN SKEGDTEEQL ALIESEEGSW
     VDSFARIVVK VPPPLVEEGL EMQKKGTQNF REIIVTMLRE WAQADFIESK DLIRCMFKLL
     LRQYSGIREI RDAMSQTYVF HERNAGDVTD FIVYLIQIRE LLTVQFEHTE EAILKRGLWK
     LMNNRIFFQH PDLMRLLSVH ENVMSIMMNI LTAQQGTVEH EGDEVKEKAP IKDASEMVVA
     CSRFLCYFCR TSRQNQKAMF EHLSFLLDNA TMLLARPSLR GSVPLDVAYS SFMDNNELAL
     ALKEEELDKV AVYLSRCGLQ PNSELITKGY PDIGWDPVEG ERYIDFLRFC VWINGENVEE
     NANLVIRLLI RRPECLGVAL KGEGQGLFSA FKEAIALSED IRLLENDSHP SLLTSGLLGE
     NPTYPSKDAE GEDYIDLGAA TLDFYSSLVD LLAKCAPDPM AIQAGKGDSL RARAILRSLI
     SLEDLGQILA LRFTIPNLAA PSLEAVRRAN AVQASHTQKA VMAHTFAMVA SLASEVSNTR
     RSQTFTSGTN LARRGLPCVE EVDTDDSKSS DYASVHTSFS SGNELFVPKA EKEKAELQLL
     NEKKYPIVQR RRSSRYNPID NTGPLPGLLP NHKGSVLLFL DRVYGIDQQD SLFTVLEQSF
     LPDLRAATMM DSPRALESDT ALALNRYLCN SVLPLLTNHS HFFADAEHHS ALLDATLHTV
     YRMNRLKSLT KNQRDAVSDF LVAITRELPP AMMIKLLKKV INDILTMNDM NVLVPLRLIT
     LHYERCGKYY GSGNHYGVAS EQEKRLSMLL FDAIFDTLGS RPYDPELFGK ALPCMTAIGS
     AISPDYTLTS GLEDVRNKKR EEEGAWIPRT VDVSRCEINR DLEKMTELFA EHFHDSWASR
     KIEKGWAHGD LYSRANKTHP RLKPFSLLKD FEKSFYKERC SECIKALMAW NYTFEMIDRD
     ANDRASAART LSGTSISNFA PKPIDLSSMT LEKDMVNAAE KMAEHSHLVW AKKVMNDLNN
     KGGFMPIPLV PWDLLTDFER RKDRFRSSEI LKFLQYHGYH VNCPKDEQSQ NDRMKSEGER
     SSVEKRFAYN LLEKLITYLE QASLKMKSVK PSQELTRRNS FKKEGQDVKF FEKVVLPLMH
     AYFNAHKNYF LEGSSIVQTG TASNKEKEMV ANLFCRLAAL LRIKNRAFGS VAKITVKCLQ
     GLTQALDLRT LVKVNSDIVR TSLLTFFNNC ADDLYAAVNE LKDGGQYSLI RGQALKSWNS
     FEFANQMIVP VLTTMFAHLA RNHFGTDLLL DDIQAACYKI LDSLYMVTGL NSSISHRKSI
     SSESEKHRPG LGQCLAAFAS CFPVAFLEPE FNKSNKFSVL AKSQDQSVQV QEMLQNLSTH
     IPHLEKLLTD LETVSNNNTM YSDVPNVYDV DLPLMCSYMA HWFSVGPDGK KDKDDQRASV
     VQTTSVSCDH INRIFNALLK MIRNHVGIEN APWLCRVNFF AVQIIQNVTS DPVREFVLPI
     AERLRRMSEK AYKEEEHMRT HPDDADEGTV AEDNARLVRD TYAFFPILMK YTDLHRAQWL
     KSPTWETDGV YENVAVIFRI WSQSQHFKRE ELNYVAQFEE DAAAMGGGDM KTGKAAIAER
     KKKRREGQDK MKEYFDRNGR PIIKKDKHAA SIVIACLKRL LPVGLNVFGG RELDIVQQSK
     EKFIQKETEE KIREFIKGLL EIPVKTDPTD KNAWQLSLYR KIGKYSCMFQ RNLAYFTGKS
     QMRGKDEMSQ EAVIEKIFNM GQVSAILHTI TRTKDRRRRA HHRWKTEHPQ MQLSQAWKKV
     VSTQRKRAVV ACFRMVPLYG IPRRTASFLR ESSLFMGSSQ LIICLLDDFS NGEGRHMEES
     AYSAKKTNGY LSHHCFSFVQ DRTSGVEEEE GPRIEIIMEE GVPIVASSEE TKEKETNPDP
     LKQLIRCFQR AATSEETAAS AIHEDSLYIR FADVMAKSIH IEEEEEDGDE GEIDQAAKEE
     QSQALRGEQA VLASRGAAIM CLMYLSASGG EPNEMVAQTL QLGIHLLSGG NVEIQKMLIE
     YLQLKKDVRF FTSMAGLMNK CSVLNLEMFE RQIKGAQVLS PHLFAFPPLS STSGRCSFPS
     TLLFVLECAE GLGMGAELAS GDNQNLNDAD FTCSLFRFLQ LTCEGHNLEF QNYLRTQPGH
     TTSVNLINCT VDYLLRLQES VMDFYWHYSS KEVIDEGGKE YFLRAIQVCS QVFNTLTESI
     QGPCVGNQMT LANSRLWDAI NGFFFLFAHM MEKLYKNSTQ LELLREFLNL QKDMIVLMLS
     MLEGNVLNGS IGKQMVDALV ESQPSVEKIL KFSDMFLKLK DLTTSQAFQD FDTNQDGWIS
     PKEFQRAMES QKMYTVEDIT YLMMCTDVNN DGKVDYMEFT ERFHNPARDI GFNLAVLLVN
     LKEHITNDPR LEKIIEKAQT LLEYFDPFLG RIEIMGSSKR VEKIYFEIQE SWLEQWGKQQ
     IRDSKNSFLF NVLQDDGGDQ GKLEAFINFC EDTIFEMQHA AAISSGDSDT KMERAIKQRD
     YFLQQTTASD HISETFKSGY NYGISAASAL SPQNISTTMR NVTTSIRQMT WTQLLYAIII
     LIIRAGMAIG WAGYLLLMTI FRFAYFLTTS SEEEEAAKQE KEQAKMNHHE HPTFNPPVIQ
     EFHHSHVGVD AFGVGMNADH LNVNSLPDFV PPPRPETPET VLSEEEKPLN QDIPSPTSPA
     AASKAPSIYE SIGAPQMVQL QSEADFQQGQ YEPKIAESNS TKTRGSILNM LARNFKTIEK
     ITLYLAFFIN VILLFHRVDI THTENPESAS EGDDDEDALE SIFITGMQFP YIEYEITGWM
     LSQILYWISV LHLSTSFALL VSFYQLKIPL ITFKREKEIA RKLMFDGCWI TEEDSEELGI
     VDTFMWYLDR IVISAKSFPM MYWDKFVRRK TRSKFKDQVD EETLTSILGE EKMSTDSSYD
     YRYSCWLWLG VILTNGQFLY RVGYLLCSAC GVFMSPFFYA FHLIDVVLSF PMLKAILQSV
     THNLQQLILT IMMTLVVVYL YTVIAFNFFR KFYVQEGEDG EEPDRKCHNM LTCFIYHFYA
     GVRAGGGIGD ELESPYGDDL EYPRMFYDIS FFFFVIIILL AIMQGLIIDA FGELRDQQES
     ATEKLESSCF ICDIGKETFD RMPRGFEIHT TKEHNFANYL FFLQHLVNKD ETEYTGQETY
     VREKYDNRDW DFFPVGECFV KQYEDQLLQS
//
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