ID   G0MYS1_CAEBE            Unreviewed;       961 AA.
AC   G0MYS1;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 56.
DE   RecName: Full=UNC-45/Cro1/She4 central domain-containing protein {ECO:0000259|Pfam:PF11701};
GN   ORFNames=CAEBREN_14621 {ECO:0000313|EMBL:EGT47902.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC       {ECO:0000256|ARBA:ARBA00004556}.
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DR   EMBL; GL379821; EGT47902.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0MYS1; -.
DR   STRING; 135651.G0MYS1; -.
DR   EnsemblMetazoa; CBN14621.1; CBN14621.1; WBGene00153346.
DR   eggNOG; KOG4151; Eukaryota.
DR   HOGENOM; CLU_007331_0_0_1; -.
DR   InParanoid; G0MYS1; -.
DR   OMA; LDQKHED; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR024660; UCS_central_dom.
DR   PANTHER; PTHR45994; FI21225P1; 1.
DR   PANTHER; PTHR45994:SF1; FI21225P1; 1.
DR   Pfam; PF11701; UNC45-central; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   4: Predicted;
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Myogenesis {ECO:0000256|ARBA:ARBA00022541};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT   DOMAIN          316..507
FT                   /note="UNC-45/Cro1/She4 central"
FT                   /evidence="ECO:0000259|Pfam:PF11701"
SQ   SEQUENCE   961 AA;  107314 MW;  3DF661BB08BF0439 CRC64;
     MVARVETAEE IRDQGNAAIK DQDYVKADEL YTEALQLTTG DDKTLRPVLY RNRALARLKR
     DDFEGAQSDC SKALEYDGAD VKALFRRALA REQLGNVGPA FNDAKEALRL SPKDKGINET
     LQRLLKANHE KVKQTTSMEN KVSDMAKLAF RGEAKDNAQK MTALNNLLVL CRESETGATQ
     VWNQSSIVSF VLNLINDKNE SEELVVTALR ILDETIKNNA RAMKFLAMHD ADGSKSVRFV
     CRLMCKRDGK DYVDAAGLLI QRVFNAMAKM DRQKEMKPDP EVAEANKLWI IRVILELQEM
     LQDPKVGILQ RETAIDLFLK NLMHMDGGIP RGWSWKFVEE RGLLTLLDVA SQIPEQCDYP
     VSAETRQHVA ICLQRLEEDM VFDTKRTIFK DKVDFFFNAL ISRATDDEEG HKYRIKLSCF
     LITMLQGPVD LGINLIINDQ LTPIMLQMAA SQNHLMQGIA AELIVGTIAK HERAINMLKV
     GIPVLRALYD SEDPTVKVRA LVGLCKIGAA GGDDISKATM KEEAVISLAK TCKKFLLETE
     KYSVDIRRYA CEGLSYLSLD ADVKEWIVDD SLLLRALVIL AKNAGALCVY TLATIYANLS
     NAFEKPKVDE EMVKLAQFAK HHVPETHPKD TEEYVEKRVR ALVEEGAVPA CVAVSKTESK
     NALELIARTL LAFAEYEDLR GRIISEGGTV LCLRLTKEAS GEGKIKAAHA IAKLGAKADP
     TISFPGQRAY EVVKPLCDLL HPDVDGKANY DALLTLTNLA SVSDSIRARI LKEKAVPKIE
     EFWFMTDHEH LRAAAAELLL NLLFFEKFYE ETVAPGTDRL KLWVLYSAEV EDERLSRASA
     AGFATLTLDE SACARIMDEI KSWPEVFKDI AMHEDAETQR RGLMGIANIM QASNKLCSEI
     VSSEVFRVLV AVTKLGGINQ ERAGSTEQAK RALDAAEKFG LIKATDRELY ERANQISTIQ
     E
//