ID   G0N275_CAEBE            Unreviewed;       450 AA.
AC   G0N275;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=CBN-VHA-19 protein {ECO:0000313|EMBL:EGT50564.1};
GN   Name=Cbn-vha-19 {ECO:0000313|EMBL:EGT50564.1};
GN   ORFNames=CAEBREN_18951 {ECO:0000313|EMBL:EGT50564.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the vacuolar ATPase subunit S1 family.
CC       {ECO:0000256|ARBA:ARBA00009037}.
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DR   EMBL; GL379829; EGT50564.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0N275; -.
DR   STRING; 135651.G0N275; -.
DR   EnsemblMetazoa; CBN18951.1; CBN18951.1; WBGene00157676.
DR   eggNOG; KOG3868; Eukaryota.
DR   HOGENOM; CLU_627482_0_0_1; -.
DR   InParanoid; G0N275; -.
DR   OMA; QIVINVR; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009992; P:intracellular water homeostasis; IEA:EnsemblMetazoa.
DR   GO; GO:0060282; P:positive regulation of oocyte development; IEA:EnsemblMetazoa.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:EnsemblMetazoa.
DR   InterPro; IPR008388; Ac45_acc_su.
DR   InterPro; IPR046756; VAS1/VOA1_TM.
DR   PANTHER; PTHR12471:SF7; V-TYPE PROTON ATPASE SUBUNIT S1; 1.
DR   PANTHER; PTHR12471; VACUOLAR ATP SYNTHASE SUBUNIT S1; 1.
DR   Pfam; PF20520; Ac45-VOA1_TM; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..450
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003404059"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          400..438
FT                   /note="V-type proton ATPase subunit S1/VOA1 transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF20520"
SQ   SEQUENCE   450 AA;  49015 MW;  A0F4D2EEF6A46453 CRC64;
     MRVLFAVFSL IVACHAYDAV LFSNQREIGG ISAEQLVKGA TPEEPIVFIV NPDFTLGQFS
     VKANAYSAEP TTDYLAKSVK NSNFHESQYF ANQIQASTAQ VLTSADQYKS GNALYIIAGE
     EWTSMEQLAE QLISKIDNSV GIITSTDAVS HEKTNRVKRV ATDEMDAANS DSTNGPQPNG
     AYAFPLVLPP YNNSGVKITP TADETCLFYL EGINIVVQQN LNKVLSYASV HIPGNNMTWS
     YAPGDAKCQN GGSIGQFIFR LRMTLTQDVS AKAGNNVAFS MKSGDLIDVS LNITGDLFGY
     WSLTGATMHN AKITAGTFKE AESVGKTIDE RATQYSKINS VAGWSLVCSS SQAVFFPTNE
     ESIQIGFSLA NTQIQTFNIQ NNKTWIANPH FTLQTEDCTG TFSAGSWMGI VSALVLIAGL
     MFGYVMLQSV QTMDRFDDPK QKQIVINVRE
//