ID G0N371_CAEBE Unreviewed; 495 AA.
AC G0N371;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN Name=Cbn-pph-5 {ECO:0000313|EMBL:EGT51403.1};
GN ORFNames=CAEBREN_24661 {ECO:0000313|EMBL:EGT51403.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PPP phosphatase family. PP-5 (PP-T)
CC subfamily. {ECO:0000256|ARBA:ARBA00008786}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL379833; EGT51403.1; -; Genomic_DNA.
DR AlphaFoldDB; G0N371; -.
DR STRING; 135651.G0N371; -.
DR EnsemblMetazoa; CBN24661.1; CBN24661.1; WBGene00163386.
DR eggNOG; KOG0376; Eukaryota.
DR HOGENOM; CLU_004962_5_2_1; -.
DR InParanoid; G0N371; -.
DR OMA; NHFFMSR; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd07417; MPP_PP5_C; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041753; PP5_C.
DR InterPro; IPR013235; PPP_dom.
DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45668; SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED; 1.
DR PANTHER; PTHR45668:SF5; SERINE_THREONINE-PROTEIN PHOSPHATASE 5; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF08321; PPP5; 1.
DR PIRSF; PIRSF033096; PPPtase_5; 1.
DR PRINTS; PR00114; STPHPHTASE.
DR SMART; SM00156; PP2Ac; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 61..94
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 202..478
FT /note="Serine/threonine specific protein phosphatases"
FT /evidence="ECO:0000259|SMART:SM00156"
SQ SEQUENCE 495 AA; 56177 MW; AC3BF2BA9214ED36 CRC64;
MAGITDDIVA TVLESIEEKK FDGDEQKAEL IKKEANQFFK DQVYDVAADL YSVAIELHPS
AILYGNRAQA YLKKELYGAA LEDADNAIAI DPSYVKGFYR RATANMALGR FRKALADYQA
VVKVAQKDLD AKAKFEECQK IVRRQAFLAA ISVDHDKKTV AETLDISKIA VEDAYEGPHL
EDKITIEFMM ELIQKFKSQK LLHKKYAFKM LLDFYNYVKT LPTMVEITVP AGKKFTICGD
VHGQFYDLCN IFEINGYPSE TNPYLFNGDF VDRGSFSVET IFTMIGFKLL YPHHFFMSRG
NHESDVMNKM YGFEGEVKSK YTQQMSDMFT ETFCWLPLCH LINEKIFVCH GGLFKEDGVT
LDDIRKVDRN RQPPDEGIMC DLLWSDPQPI SGRSASKRGV GCQFGPDVTS KWCEANGIEY
VVRSHEVKPE GYEMHHNGQC FTVFSAPNYC DQMNNKGAFI TITGDNLTPR FTPFDAVPHP
KLPPMAYANS LFGFN
//
