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Database: UniProt
Entry: G0NB47_CAEBE
LinkDB: G0NB47_CAEBE
Original site: G0NB47_CAEBE 
ID   G0NB47_CAEBE            Unreviewed;       783 AA.
AC   G0NB47;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   05-JUL-2017, entry version 24.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=CAEBREN_30288 {ECO:0000313|EMBL:EGT56751.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; GL379856; EGT56751.1; -; Genomic_DNA.
DR   STRING; 135651.CBN30288; -.
DR   EnsemblMetazoa; CBN30288; CBN30288; WBGene00192253.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   InParanoid; G0NB47; -.
DR   OrthoDB; EOG091G01BI; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 2.
DR   PIRSF; PIRSF001293; ATP6V0A1; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008068};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    270    294       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    315    333       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    410    427       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    448    468       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    528    547       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    567    588       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    711    735       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   783 AA;  88766 MW;  A32FE497DFA39963 CRC64;
     MIASSAESSG ISDVLSADEE ELTARFSDAM SPLKLQLRFV AGVIQRERLP AFERLLWRAC
     RGNVFLRTSE IDDVLNDTVT GDPVNKCVFI IFFQGDQLKT KVKKICEGFR ATLYPCPDTP
     QERREMSIGV MTRIEDLKTV LGQTQDHRHR VLVAASKNVR MWLTKVRKIK SIYHTLNLFN
     IDVTQKCLIA EVWCPIAELD RIKMALKRGT DESGSQVPSI LNRMETHEAP PTYNKTNKFT
     KGFQNIVDAY GIATYREINP APYTMISFPF LFAVMFGDMG HGVIMFLAAL FFILKEKQLE
     AARIKDEIFQ TFFGGRYVIF LMGVFSIYTG FMYNDVFSKS INTFGSSWRN SIPESVIDKY
     LDTEKGGETQ LMLFPELAFD GNPYPIGVDP VWNLAEGNKL SFLNSMKMKM SVLFGIAQMT
     FGVLLSYQNY TYFKSDLDIK YMFIPQMVFL SAIFIYLCLQ IIAKWLFFGP FATTVLGYTY
     PGTNCAPSLL IGLINMFMMK SRNAGFVDEH GEQLPQCWLS TWYPGQSFFE TIFVLVAIAC
     VPVMLFGKPY FLWKEEKERR EGGHRQLATI EVVLVVLALV QVPIMLFAKP YFLYHRKKQS
     QVRYSTLNDA ATTSNQQSVR ADIAQDDAEV VHAPEQTPKP AGGHGHGHGD GPLDMGDVMV
     YQAIHTIEFV LGCVSHTASY LRLWALSLAH AQLSDVLWTM VFRNAFVLDG YAGAVATYVL
     FFIFGSLSVF ILVLMEGLSA FLHALRLHWV EFQSKFYGGL GYEFAPFSFE KILAEEREAE
     ENL
//
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