ID G0NBN7_CAEBE Unreviewed; 258 AA.
AC G0NBN7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Gem-associated protein 2 {ECO:0000256|PIRNR:PIRNR038038};
GN Name=Cbn-smi-1 {ECO:0000313|EMBL:EGT57135.1};
GN ORFNames=CAEBREN_24689 {ECO:0000313|EMBL:EGT57135.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The SMN complex catalyzes the assembly of small nuclear
CC ribonucleoproteins (snRNPs), the building blocks of the spliceosome,
CC and thereby plays an important role in the splicing of cellular pre-
CC mRNAs. {ECO:0000256|PIRNR:PIRNR038038}.
CC -!- SUBUNIT: Part of the core SMN complex. {ECO:0000256|PIRNR:PIRNR038038}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the gemin-2 family.
CC {ECO:0000256|ARBA:ARBA00025758, ECO:0000256|PIRNR:PIRNR038038}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL379859; EGT57135.1; -; Genomic_DNA.
DR AlphaFoldDB; G0NBN7; -.
DR STRING; 135651.G0NBN7; -.
DR EnsemblMetazoa; CBN24689.1; CBN24689.1; WBGene00163414.
DR eggNOG; ENOG502QPK4; Eukaryota.
DR HOGENOM; CLU_053222_0_0_1; -.
DR InParanoid; G0NBN7; -.
DR OMA; WTLRCEL; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0032797; C:SMN complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:EnsemblMetazoa.
DR GO; GO:0000245; P:spliceosomal complex assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0000387; P:spliceosomal snRNP assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.58.1070; -; 1.
DR InterPro; IPR017364; GEMIN2.
DR InterPro; IPR035426; Gemin2/Brr1.
DR PANTHER; PTHR12794:SF0; GEM-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR12794; GEMIN2; 1.
DR Pfam; PF04938; SIP1; 1.
DR PIRSF; PIRSF038038; SMN_Gemin2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR038038};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|PIRNR:PIRNR038038};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW ECO:0000256|PIRNR:PIRNR038038};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 258 AA; 29647 MW; C33C28BC581E6B4D CRC64;
MDQEACLGPD STDLEDVDAD PNAPAMSAAA YFRQMKAERK AAANVVRVSR NERSVSPEAK
KKKKQWLESV GYQKEEDVTT KKNISTLVPS EEWRVKRCRQ FGEFRAETAA KIATTKPMII
KELRAPQEEN WHEILLEKCL PQFQNVVDKF PNHTGTPPSW QMVFAIPKKH LSQLIEYLID
WSEEEGLSRP IREWIYVLLL VIDLPLVQDV ISALRTLLKD CRKLRSQLTP DRKSEADEYS
LFITIIGNFF GQKDLADV
//
