ID G0NZF1_CAEBE Unreviewed; 843 AA.
AC G0NZF1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGT41169.1};
GN ORFNames=CAEBREN_32284 {ECO:0000313|EMBL:EGT41169.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL379989; EGT41169.1; -; Genomic_DNA.
DR AlphaFoldDB; G0NZF1; -.
DR STRING; 135651.G0NZF1; -.
DR EnsemblMetazoa; CBN32284.1; CBN32284.1; WBGene00194249.
DR eggNOG; KOG0891; Eukaryota.
DR HOGENOM; CLU_001279_0_0_1; -.
DR InParanoid; G0NZF1; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05170; PIKKc_SMG1; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR003152; FATC_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR014009; PIK_FAT.
DR InterPro; IPR039414; SMG1_PIKKc.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF71; SERINE_THREONINE-PROTEIN KINASE SMG1; 1.
DR Pfam; PF02260; FATC; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR SMART; SM01343; FATC; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51189; FAT; 1.
DR PROSITE; PS51190; FATC; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..55
FT /note="FAT"
FT /evidence="ECO:0000259|PROSITE:PS51189"
FT DOMAIN 276..620
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT DOMAIN 811..843
FT /note="FATC"
FT /evidence="ECO:0000259|PROSITE:PS51190"
SQ SEQUENCE 843 AA; 96604 MW; ABCC281CE8415F51 CRC64;
MSIQLLIISE ILPQLFARLS HPSDHIRKTL VDLISRICTA APHAVVFQVV SGAASSTSTE
IGEDLEEQHN DDRNRVQACC EQLQTKMAQS YPSLVRDVSL FVAELERINL LNEEKWSVVL
GTMEHEMEKR LTLIRTENNK TEMAMHLMPA MKDDIIAKKT ILLTRQIFDV LDDLYQQTVI
ERPKTKNEEE FVTTFAELLT NAHQESRQSR LISPEKSWAP FKNLIANFVH RNIKKGMQLF
ETEEISPYLA NLVNSCVPMP GQESVEFDRV VSIARVSKQV TILPTKTRPK KLGFIGSDGK
QVAFLFKGRE DLHLDERVMQ FLRLCNVMLQ PGKGKTRQIA EYQAHHYAVI PLGPRSGLIK
WVEGATPIFH IYRKWQMKEK ALKQASKKSG ETVPDVERPS NMYHNMMRES FNAHKIDATV
AADRTKWPLY IYEEVFAGLC EKTPTDLISR ELWMKSNDAN TWWSVTKRYA RSLAVMSMIG
SVLGLGDRHL DNLLVDLKWG HVVHIDYNIC FDKGKNLRIP ETVPFRLSRN MRHALGPSEM
YGTFRESCVH VLSTLRSGHQ VLTMLLDAFV FDPLVDWTSH EHSSTSGVSL ALQLAVYGSG
WKSKARERLT DTMELLQLRM NEMQSLWKNN RDDLLLWMKQ VTDCLMLEKS MLGANGIYAQ
QRVKAGTELR EAVTRHQALA KELRPLIRAI GKEREEFAEY MKFYKRGFID PLLKGHSALR
HEVDIDTCVQ NFNIVMQNID IVFGSLVNLS SMPIETITAR TPQQQFKAPP GLENVWIVNQ
DQQENSQARE VVKRVERRLN GWLDGSATTD RKMSPREEVD HLIAEATSTT NLSQMYEGWT
AWV
//
