ID   G0PFN2_CAEBE            Unreviewed;       581 AA.
AC   G0PFN2;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN   ORFNames=CAEBREN_06224 {ECO:0000313|EMBL:EGT54035.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
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DR   EMBL; GL380379; EGT54035.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0PFN2; -.
DR   STRING; 135651.G0PFN2; -.
DR   EnsemblMetazoa; CBN06224.1; CBN06224.1; WBGene00144949.
DR   eggNOG; KOG3867; Eukaryota.
DR   HOGENOM; CLU_006332_13_3_1; -.
DR   InParanoid; G0PFN2; -.
DR   OMA; MKWHHGH; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd16160; spARS_like; 1.
DR   Gene3D; 3.30.1120.10; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR43751; SULFATASE; 1.
DR   PANTHER; PTHR43751:SF2; SULFATASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   Pfam; PF14707; Sulfatase_C; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..581
FT                   /note="Sulfatase N-terminal domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003406893"
FT   DOMAIN          37..359
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
SQ   SEQUENCE   581 AA;  65609 MW;  2CAF132F0924FE11 CRC64;
     MSPVSLLHLL LLIFPLSAQQ ELRQEECTVQ PPSPRHPNIV VLMIDDLGYG DIAAYGHPTQ
     EYTQVDRMAA EGTRFTQAYS ADSMCSPSRA GFITGRLPIR LGIVGGRRVF VPYDIGGLPK
     TETTMAEMLK EAGYATGMVG KWHLGINENN ATDGAHLPSK RGFDYVGVNL PFTNVWQCDT
     TKEFYDKGPD PSLCFLYDGD DIVQQPMKFE HMTENLVGDW KRFLMTRLAQ DQHERPFFFY
     FSFPQVHSTQ FASKRFRGSS VRGIYGDSIN EMSWAVGEVL DSLVNAGIAE NTLVILMSDH
     GPHVELCLNG GSTAGLKGGK SNSYEGGFRI PFIAWQPGTV KPARVSHEVI SSMDLFPTFR
     AMNDECLFEK EPLRSDGINI ADELRGETDD VEGSLGKARP IIYYCNTHLM AIRIGDYKVH
     YKTSPIFLNT SVDPNLDYFC PNGKPKSDWY VSQVCPDEHL QKHYPPLVFD LIRDPYEQYP
     LQNTVKSQEV SFWENIFFRK SVFQIRFQAM QRLTEHKSSL VKVKNVLGNF NKTLIPCCNP
     PSCKCDKLSR PSELSDGGRP DYVGLVPDLD RTEYELLNRF F
//