ID   G0PK10_CAEBE            Unreviewed;       566 AA.
AC   G0PK10;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGT60541.1};
GN   ORFNames=CAEBREN_28776 {ECO:0000313|EMBL:EGT60541.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC       family. {ECO:0000256|ARBA:ARBA00008685}.
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DR   EMBL; GL380783; EGT60541.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0PK10; -.
DR   STRING; 135651.G0PK10; -.
DR   EnsemblMetazoa; CBN28776.1; CBN28776.1; WBGene00190741.
DR   eggNOG; KOG1052; Eukaryota.
DR   HOGENOM; CLU_007257_0_1_1; -.
DR   InParanoid; G0PK10; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966:SF561; GLUTAMATE RECEPTOR FAMILY (AMPA); 1.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        171..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        418..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          48..415
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
FT   DOMAIN          58..115
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
FT   REGION          485..513
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   566 AA;  64761 MW;  8B778AAF6C3698FC CRC64;
     MYVLKLMNEC RKALGNWSEK RGWNFDSRYA NRWEFDIDPD SEDLEGLHLR VVVYLEEPFV
     IKTGENQYEG FCIDLLNEMT KVLKFNYTII EVQDGTYGIE DESGRWNGII GALQRHEADL
     SLSAVTITYS RAEVVDFTLP FMHLGISILL ARTSEETDKG SLWTFLEPLS LTVWISLLIS
     YCIVSYSMHI LAKFSPYEWY NLERIDERDF ENIKNQKNQF TILNSFWFTM GSLMQQGSDV
     IPRAAATRLI AVVWWMFTQI IISSYTAQLA AFLTVERMST PIESTQDLAN QQKIRYGVLK
     SGSTMDFFRE SKIPMYERMW SVMESSSPGV FVNSSREGIA RVKSGGYAYM MESSMLEYYL
     ERDCDLQSIG GLLDSKGYGI ALPKGSPLRD ILSRTVLQLQ ERTILEALKN KWWRDRRGIF
     YVLLTGLIVA FLLACGEYCI ESRHEAFRLK LTIVGKFIDW YRGNSNDTKV RSKMRNMQLD
     TAGQEIAISS RPEPPPQPVA TSRPDPTRLS ISSPAPTICV VSCDDGTPIS RDRPPSISRA
     GLRRLSRMLP ATTHEQLSRF RQGSMS
//