ID G0PKT3_CAEBE Unreviewed; 371 AA.
AC G0PKT3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=FAD synthase {ECO:0000256|ARBA:ARBA00012393};
DE EC=2.7.7.2 {ECO:0000256|ARBA:ARBA00012393};
DE AltName: Full=FAD pyrophosphorylase {ECO:0000256|ARBA:ARBA00031145};
DE AltName: Full=FMN adenylyltransferase {ECO:0000256|ARBA:ARBA00031871};
GN ORFNames=CAEBREN_08097 {ECO:0000313|EMBL:EGT33011.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + FMN + H(+) = diphosphate + FAD; Xref=Rhea:RHEA:17237,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:57692, ChEBI:CHEBI:58210; EC=2.7.7.2;
CC Evidence={ECO:0000256|ARBA:ARBA00001332};
CC -!- PATHWAY: Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step
CC 1/1. {ECO:0000256|ARBA:ARBA00004726}.
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DR EMBL; GL380929; EGT33011.1; -; Genomic_DNA.
DR AlphaFoldDB; G0PKT3; -.
DR STRING; 135651.G0PKT3; -.
DR EnsemblMetazoa; CBN08097.1; CBN08097.1; WBGene00146822.
DR eggNOG; KOG2644; Eukaryota.
DR HOGENOM; CLU_030805_8_0_1; -.
DR InParanoid; G0PKT3; -.
DR OMA; DEESAEC; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd01713; PAPS_reductase; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR002500; PAPS_reduct.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR23293:SF9; FAD SYNTHASE; 1.
DR PANTHER; PTHR23293; FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE; 1.
DR Pfam; PF01507; PAPS_reduct; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 181..336
FT /note="Phosphoadenosine phosphosulphate reductase"
FT /evidence="ECO:0000259|Pfam:PF01507"
SQ SEQUENCE 371 AA; 42527 MW; 592BDEA8ED82DC79 CRC64;
MSQLLWGTQK FNGAISTFPV VRVANVVALP GVPKFCERAF DELQDQLFPV EERQSMFFDT
IYTDLDEFDF SRKLTDLAAR FEEKNVQIGS YPELKNKFFK TKLTIEAESP ESMEAVVAAL
RELLTGHLVY YDSYAWTDTV AKWKAFKKRE TAENHLEFVR KLEEAEKIVE DIVEKYPLDQ
IGLSFNGGKD CTVLLHLLRL KVDEKYGPST PIQGFHIMVE DQFPEATQFI IDAAKFYNIQ
VLEFPGPLKT GLASLKKTRP SIVPVLMGSR ATDPNGKYMK TPVEWTDSDW PRVLRVCPIL
NWTYTDVWHM LRGLCVPYCQ LYDQGYTSLG GRDNTVKHPA LRIVSSDGKE HYLPAYKLHD
DAAERCNRSN L
//
