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Database: UniProt
Entry: G0QV19_ICHMG
LinkDB: G0QV19_ICHMG
Original site: G0QV19_ICHMG 
ID   G0QV19_ICHMG            Unreviewed;       639 AA.
AC   G0QV19;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   07-JUN-2017, entry version 19.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
DE   Flags: Fragment;
GN   ORFNames=IMG5_120760 {ECO:0000313|EMBL:EGR30944.1};
OS   Ichthyophthirius multifiliis (strain G5) (White spot disease agent)
OS   (Ich).
OC   Eukaryota; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Ophryoglenina; Ichthyophthirius.
OX   NCBI_TaxID=857967 {ECO:0000313|Proteomes:UP000008983};
RN   [1] {ECO:0000313|EMBL:EGR30944.1, ECO:0000313|Proteomes:UP000008983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G5 {ECO:0000313|EMBL:EGR30944.1,
RC   ECO:0000313|Proteomes:UP000008983};
RA   Coyne R., Brami D., Johnson J., Hostetler J., Hannick L., Clark T.,
RA   Cassidy-Hanley D., Inman J.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; GL983929; EGR30944.1; -; Genomic_DNA.
DR   RefSeq; XP_004032531.1; XM_004032483.1.
DR   EnsemblProtists; EGR30944; EGR30944; IMG5_120760.
DR   GeneID; 14907069; -.
DR   InParanoid; G0QV19; -.
DR   Proteomes; UP000008983; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008983};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008983};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM     46     66       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    201    220       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    400    416       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    600    616       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   DOMAIN      309    557       Hydrolase_4. {ECO:0000259|Pfam:PF12146}.
FT   NON_TER     639    639       {ECO:0000313|EMBL:EGR30944.1}.
SQ   SEQUENCE   639 AA;  74153 MW;  81270FE65602092E CRC64;
     MDFMIFLKWS SDWSTYNNQP SIITLMINLP LKGADPGEVP LWGDGTIVSI ICILIMLIPK
     PLLIYYDQKR KYKKVNKRGS RNQMQLQQQL RAFQQMNLLN ANIDQVNNDH KDEHSDEEKD
     IEIQVHSNPQ KDILQESEHK EEESLGELFI HQIIETIEFA LGSISNTASY LRLWALSLAH
     EQLAEVFFEK GIKSSIENGD IVGLFFGFLI FAIATFGVLM CMDIMECFLH TLRLHWDLFN
     KFIKISDNNY NQPPPKNLQD NINQLFDQDK DKFIGEFVCD DYVIIRGYIN GTGKQLRLYY
     TKLEPKQGKK ATICIVHGFG EHSGRFLHIA DRFAKVGFVV QLVDLRGFGY SGGPRGASTI
     EELHQDICTL LKQANKDLPL YLYGHSLGGQ LVITLVMRNP LLNIAGVIIT SALIGFPKDR
     KINFLKTFLL KSLGKKLEDI VVNSMIHPTA LTKNDEYIKK CFGDRLMIPF LGMNMAKNIL
     EGIEYVIPNA FKFQFPCIII HGQKDMVTNH HDSIAFYNKC SRFFFLFFLY FFNINEISID
     KTLKLFENGY HELQHDDEFE ELIECIICWI NQRYTNAKNF GLIGQIKCGL KRYNKKSRKY
     KFALFFLILI YIYYLYKFRQ HSLFGKQQKK ILLSPFLNL
//
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