ID G0RBX6_HYPJQ Unreviewed; 280 AA.
AC G0RBX6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=S-adenosyl-L-methionine-dependent methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIREDRAFT_2591 {ECO:0000313|EMBL:EGR51402.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR51402.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR51402.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. BUD23/WBSCR22 family. {ECO:0000256|ARBA:ARBA00005547}.
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DR EMBL; GL985058; EGR51402.1; -; Genomic_DNA.
DR RefSeq; XP_006962489.1; XM_006962427.1.
DR AlphaFoldDB; G0RBX6; -.
DR SMR; G0RBX6; -.
DR STRING; 431241.G0RBX6; -.
DR EnsemblFungi; EGR51402; EGR51402; TRIREDRAFT_2591.
DR GeneID; 18484335; -.
DR KEGG; tre:TRIREDRAFT_2591; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_2591; -.
DR eggNOG; KOG1541; Eukaryota.
DR HOGENOM; CLU_055194_0_2_1; -.
DR OrthoDB; 5486608at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:EnsemblFungi.
DR GO; GO:0043527; C:tRNA methyltransferase complex; IEA:EnsemblFungi.
DR GO; GO:0016435; F:rRNA (guanine) methyltransferase activity; IEA:EnsemblFungi.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0070476; P:rRNA (guanine-N7)-methylation; IEA:EnsemblFungi.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR039769; Bud23-like.
DR InterPro; IPR022238; Bud23_C.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12734:SF0; 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR12734; METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR Pfam; PF12589; WBS_methylT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008984};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 52..160
FT /note="Methyltransferase type 11"
FT /evidence="ECO:0000259|Pfam:PF08241"
FT DOMAIN 221..277
FT /note="18S rRNA (guanine(1575)-N(7))-methyltransferase
FT Bud23 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12589"
SQ SEQUENCE 280 AA; 30300 MW; 7B314056BA93789B CRC64;
MSRPEDSLAA DVHYDDTEAR KYTTSSRIQN IQASMTRRAL ELLDLKSPSL ILDVGCGSGL
SGEILSAVDP SDGGPHTWIG MDVSPSMLDI ALQRDVEGDL LLADIGQGVP FRAGTFDAAI
SISAIQWLCS AESSETSPTG RLNRFFNGLY ASLRRGGRAV CQFYPKNDTQ RNMITQAAVK
AGFGAGILED DPGTKNVKLY LVLTVGNNGG EGGNTDITGV VDGMDNVDVL DARKRLKANN
AQLKKGSKAW IVKKKEQMER KGKIVKATSK YTGRKRRVQF
//
