ID G0TCN1_9CALI Unreviewed; 86 AA.
AC G0TCN1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE SubName: Full=RNA-dependent RNA polymerase {ECO:0000313|EMBL:AEK64864.1};
DE Flags: Fragment;
OS Norovirus pig/GII.11/SII-2-45/2008/Tw.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX NCBI_TaxID=984327 {ECO:0000313|EMBL:AEK64864.1};
RN [1] {ECO:0000313|EMBL:AEK64864.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Pig/GII.11/SII-2-45/2008/Tw {ECO:0000313|EMBL:AEK64864.1};
RA Chao D.-Y., Wei J.-Y., Chang W.-F., Wang J., Wang L.-C.;
RT "Molecular identification of multiple genotypes of Norovirus and Sapovirus
RT in swine in Taiwan.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEK64864.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Pig/GII.11/SII-2-45/2008/Tw {ECO:0000313|EMBL:AEK64864.1};
RX PubMed=22489630; DOI=10.1111/j.1863-2378.2012.01483.x;
RA Chao D.Y., Wei J.Y., Chang W.F., Wang J., Wang L.C.;
RT "Detection of multiple genotypes of calicivirus infection in asymptomatic
RT Swine in taiwan.";
RL Zoonoses Public Health 59:434-444(2012).
CC -!- FUNCTION: Viral genome-linked protein is covalently linked to the 5'-
CC end of the positive-strand, negative-strand genomic RNAs and subgenomic
CC RNA. Acts as a genome-linked replication primer. May recruit ribosome
CC to viral RNA thereby promoting viral proteins translation.
CC {ECO:0000256|ARBA:ARBA00025359}.
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DR EMBL; GU556170; AEK64864.1; -; Genomic_RNA.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000313|EMBL:AEK64864.1}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 1..86
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEK64864.1"
FT NON_TER 86
FT /evidence="ECO:0000313|EMBL:AEK64864.1"
SQ SEQUENCE 86 AA; 9289 MW; 83520D6470042610 CRC64;
MVKFSAEPEL AQVVAEDLLA PSVLDVGDFR ISIVEGLPSG VPCTSQWNSF AHWLITLCAM
SEVTGLSPDV IQAHSCFSFY GDDEIV
//
