ID G0TZV3_TRYVY Unreviewed; 735 AA.
AC G0TZV3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=ubiquitinyl hydrolase 1 {ECO:0000256|ARBA:ARBA00012759};
DE EC=3.4.19.12 {ECO:0000256|ARBA:ARBA00012759};
GN ORFNames=TVY486_0807380 {ECO:0000313|EMBL:CCC50131.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCC50131.1};
RN [1] {ECO:0000313|EMBL:CCC50131.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCC50131.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
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DR EMBL; HE573024; CCC50131.1; -; Genomic_DNA.
DR AlphaFoldDB; G0TZV3; -.
DR VEuPathDB; TriTrypDB:TvY486_0807380; -.
DR OrthoDB; 170033at2759; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR13367:SF35; RANBP2-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13367; UBIQUITIN THIOESTERASE; 1.
DR Pfam; PF00641; zf-RanBP; 1.
DR SMART; SM00547; ZnF_RBZ; 3.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 599..628
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
SQ SEQUENCE 735 AA; 82187 MW; ABF41615C3AF3E6A CRC64;
MANVWRKKAL KCLLEDCTYA REHRDLYSQL TRSQRFYRER PTSAFHDGSN SGTFTPNTSL
LRASICEFRE SVEYPLDSFI GKSVPFLQKL RTRIGEKSLE LLSAGIDEGL RDAQGLVSEL
LQRLESTLAV GSVAGNTEAI ASVPDVPMNF DSEVVHEQEA EEEQEQETEQ EEQRVSVLPR
DDEFQIPWHV STLRLRVVEG ARPVGSQKGC CFYPLQRLRL RQEQPLLNID SRIQVSDNYY
REEWHGVGER LLKNAFLFLE WAPLAFGGAN KECSGAENSS VAAQDGICRG LVSLAEGETL
RWMIHHPSRH VAGVCMAIRL VRSGRWLDAT HSFVRAFPHP MKRQRQQLLS SVTQPSPHAP
TECSSTALAS RLIEGDGPAL IYRFFNSEMF FHPTEIKVLE DMLKDVLHAD RLAFFTECLR
ARRRHRNCWD NTPVSTLFVP PNMKEHARPL AILSTIRSRF ELLCEKLTKT PQTPVAIVQL
ESFHSRLGAL LAEAEHNTGP RAASTLLSTL MTPVAQLLYD VFSATLKPLT AADVSSALQY
LISSSENSAL PKIADYKQGS AEESATCVLQ NLLAQAFPVL RPEFLQSCHA LMSACQQPQD
EPWECPLCTL SNEPSARQCA VCDTVRTTNT TDKSDNGLNN SEPLDEAWAC PQCTFINSSL
HLETCSVCLA PNPTPLRDER RQCPGNVPPA SSWSCPDGYW ACLVEHGGCS KFNPNSVFYC
QVCDKARPGL ATLRF
//
