ID G0U1C5_TRYVY Unreviewed; 666 AA.
AC G0U1C5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=WW domain-containing protein {ECO:0000259|PROSITE:PS50020};
GN ORFNames=TVY486_0804880 {ECO:0000313|EMBL:CCC49880.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCC49880.1};
RN [1] {ECO:0000313|EMBL:CCC49880.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCC49880.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; HE573024; CCC49880.1; -; Genomic_DNA.
DR AlphaFoldDB; G0U1C5; -.
DR VEuPathDB; TriTrypDB:TvY486_0804880; -.
DR OrthoDB; 5480520at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd00201; WW; 3.
DR Gene3D; 2.20.70.10; -; 4.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR17616:SF8; YES-ASSOCIATED PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR17616; YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER; 1.
DR Pfam; PF00397; WW; 3.
DR SMART; SM00456; WW; 3.
DR SUPFAM; SSF51045; WW domain; 3.
DR PROSITE; PS01159; WW_DOMAIN_1; 3.
DR PROSITE; PS50020; WW_DOMAIN_2; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 504..532
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 571..599
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 632..666
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 272..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 72115 MW; 4C06EB5B151B3BCB CRC64;
MFLHLIVDGG YFLSGMQPTS EEAVRVAVEE INKAIREQLQ LGTETVSTVE QRVMFFSSAT
MKVLQQRQQR DVLMATLRRL RFQVVVLDCI PGSAGSPVDA AMCTRTMSAL SKSTAHSLSS
PGATVPAGHT TFVYMTSNAY VNTALEWVQS AGCGICFVVY SGDLLADELL VYAGPTVGNC
NGVATVKKGD GVGITSTLEV VGRTLHELEQ KEGKEMPLGV LTRLKQLQRQ LAQGDVTVDG
YECSFALSDD FGPSDTVGRN CGVGNVADAH EESNLRSENT QGAFVAPKNP GKELYDTSDN
RAATEGIQFE DVGRLKAKEG NASGLESVVE SPPGFTQSRA PQLVESQCAA GQLASVPQQQ
TASQMAPEVK QSVLSLGSAP HTSAATAAAS AHQQPSSTLP SSSNLPEAAE PPVSTSLPSG
WTLMFDRHRQ RHYFVFKDPS GAVSTTWMHP GGAAHQMELE RQVEVWCKEQ QQKQLLLQQG
GQSHLTPATG AAPNAPLPVS QGDWVEHVDT KTGRKYYVNH RTRQTSWTIP ADASVDQSGS
MNRSGDYVPI NAPSSSHTAM NQAGIKVIQF WEKHMDPKTG RPFYVNRQTR ETTWAPPPPV
TNTKPAQSQP LPVQQTATGA VPATVVPTPQ RADLLPFWEE HFDPNVGRSF YVNQQTRETT
WVRPCR
//
