ID G0U4A5_TRYVY Unreviewed; 397 AA.
AC G0U4A5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Zinc finger protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TVY486_1013110 {ECO:0000313|EMBL:CCC52268.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCC52268.1};
RN [1] {ECO:0000313|EMBL:CCC52268.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCC52268.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
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DR EMBL; HE573026; CCC52268.1; -; Genomic_DNA.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23164:SF28; -; 1.
DR PANTHER; PTHR23164; EARLY ENDOSOME ANTIGEN 1; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00641; zf-RanBP; 2.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00547; ZnF_RBZ; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 3.
DR PROSITE; PS50199; ZF_RANBP2_2; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00322}.
FT DOMAIN 141..172
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 202..233
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 252..283
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 334..392
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 120..147
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 42994 MW; 5D8314685F3A3AF3 CRC64;
MLRQTAMPTH GVHQQSESIH YAPGAHGVAP PSSAIFPPSM YSGVCVTPQP AFAPPTSSAV
HYNSVYGQLP ASQFVPYPMA TTTGVPAAQS HSLVVTGPSI PAAKTGASTL TQEEEDLKHL
EKIVQLRKEL EREREMEKKK RKELETWECP SCTYRNALST NQCEMCSTVR PGYNPPVSAA
ESVSRRGSQT SQTLRISPSA SFAGPTAWIC SVCLAPNEAH NARCKVCSSY QKNGTPIASP
NTATLSVAAP RAMGCWAWLC SICGSKNGAS DSRCVNCKSY QSNGTPIVDG SVTALXXXCE
MCSKPRPIQV KIPQGVSEIL GVREDSDTVQ WQDDNAASDC NRCHQQFNFA RRKHHCRACG
YVFCDACSMF RLALNRGGPK DRVCTSCYEA RMKSGHT
//
