ID G0U836_TRYVY Unreviewed; 388 AA.
AC G0U836;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE RecName: Full=NF-kappa-B-activating protein C-terminal domain-containing protein {ECO:0000259|Pfam:PF06047};
GN ORFNames=TVY486_1010880 {ECO:0000313|EMBL:CCC52045.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCC52045.1};
RN [1] {ECO:0000313|EMBL:CCC52045.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCC52045.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- SIMILARITY: Belongs to the NKAP family.
CC {ECO:0000256|ARBA:ARBA00009313}.
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DR EMBL; HE573026; CCC52045.1; -; Genomic_DNA.
DR AlphaFoldDB; G0U836; -.
DR VEuPathDB; TriTrypDB:TvY486_1010880; -.
DR OrthoDB; 2883730at2759; -.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR InterPro; IPR040466; NKAP.
DR InterPro; IPR009269; NKAP_C.
DR PANTHER; PTHR13087; NF-KAPPA B ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR13087:SF0; NKAP_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF06047; Nkap_C; 1.
PE 3: Inferred from homology;
FT DOMAIN 297..379
FT /note="NF-kappa-B-activating protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06047"
FT REGION 153..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 388 AA; 43486 MW; 7758B338AD6A33B5 CRC64;
MGRKPSTAVR YHCNYQLFLN HVHIPLHSCP YLYSILYPSL WRTEGQGEVC SEQKGVILMS
SNSAFWYPAS KPSSEELQHV LLTTVARNIF CTHHASATQE LARLKRKRKH EECGVDGPSI
GGGKEEEEVV GTLTAFDTIT FLVRASGICC ESQKRPNNSR SKLPLPQTDN GASTEQPDND
KSLKDERGTT DPPKTRSVLA SLIEGARAKE RLTAKRDLND RGDGRDVRER TALKAFEVAS
MRTSSSISRG DNLASGGDGD EFDVDLPLDP HIREDAPSAS QVEGLSTKHP LQMTREEFLC
QFKRAPRRGE IGYDAESVAA AEAVGYVMSG SRNKEKQHYV DRIQQKLHEK EARKLRLQFR
KVEDERNDRA TVESLLMMMH QKMNTGND
//
