ID G0UKR0_TRYCI Unreviewed; 2536 AA.
AC G0UKR0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Uncharacterized protein TCIL3000_4_470 {ECO:0000313|EMBL:CCC89965.1};
DE Flags: Fragment;
GN ORFNames=TCIL3000_4_470 {ECO:0000313|EMBL:CCC89965.1};
OS Trypanosoma congolense (strain IL3000).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Nannomonas.
OX NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCC89965.1};
RN [1] {ECO:0000313|EMBL:CCC89965.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IL3000 {ECO:0000313|EMBL:CCC89965.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
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DR EMBL; HE575317; CCC89965.1; -; Genomic_DNA.
DR VEuPathDB; TriTrypDB:TcIL3000_4_470; -.
DR OrthoDB; 168388at2759; -.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF343; DYNEIN AXONEMAL HEAVY CHAIN 10; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1898..2035
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2177..2445
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 1286..1313
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 2536
FT /evidence="ECO:0000313|EMBL:CCC89965.1"
SQ SEQUENCE 2536 AA; 291877 MW; 0A6E58872E3CD579 CRC64;
MNGDAVMDCV CDPRLEWFAA RIKSCLWGVT DEDINELYNE PEFLSQILAV FDTEREAFIA
VTAPPVLSGD KQQDPLSRGR LGGVLTDRGR LTVTSNAIRN VNITDSANYA QDRTRCLFFV
RLEYVKLSQE AVKDWKTDPE CPIHKAFEIS GMVVPSLVTL LTILKHVYKP LVEDVEVGAG
KTKFLASKKV VNRYLYTEIL NWVNRIEMQM TGFRSQVCAE RRLIIPQILL SMENSDAGIS
SVLSNEDIIR QVDVTVGQWQ TEISLAMSLD PQKEGPLGEI EYWREKYSTI SALYEQVNSP
EAKLIMRVAK EADCNSYHLI SSTIQQFFRH YAEAKDNVKF LGTLDRHFRT LHGVVPGSGS
LQPIIDTLSS MMTGIRMVWI ISRYYCTEER MVGLLEKIGK LIASKIAQHL DFHRVLSLPF
AEAKVVVKEG QQCLLKWKAS YLTTQEEVNA NEREQPWNFN QKRLFETTDY MSDRCTDLLE
VIETVEYYNT VLGAQLKTVL TDSSGIEKIL KDVERVKRPF ESLTFDPFER KATHNWQLVF
SNFVNMVANL DHEVSDFINK IFDDDLRSAE SAFELLLSFK CIGSRPQRVG EAFDTTSLLL
EKADRILAQF FSEVNRVRSI FDKLKGNPPL TKNQPPVAGA IHWSTSLFQR LKKPIIRFQQ
EGMLNTHMGR QVRARYSEVA QQMKEYATSR FLQWSERVRQ SSTASLKMNI IIRESDNTYV
TNFDTELFNL IRESKYLDRL GFEVPQEALN VTLQDESYHA NVDALKAMLL NFNYELQSAL
EGPERVILAK NIRELREALE PGLEDINWTS LGIPDFVLNC ERAITKFRNL SREVRKRADH
IQTQVVNRIG STRLMPEYKR LLQAGGELPE LQVLVETIER RRADLVDACV RAYSTAKPLL
TKVESQLVGT HTGKCLILES YYHHWEQRIW RAVTKMVLNS LASFAKMLGY RTHSNSPKRP
PLFKVMIFLT TEPTYSPPQQ EITSAFHKVQ TGIIASTQRF RRWMRGTCIE FTQGELVPRP
LEGEHETLFT YYQDINNLPQ VYRLQAIINR VIQTHLSSLA TNITLLQRYR FVFLADKKLS
VEQQAKSQFH WIDYDAKFQL YFNMIADFDS EKHIHDFGFM RCDESPFYLD LVEHVHQWIA
MEGAQLNETV RTRMQKRYSK IVRVNQDLEK PCEKIDDLKF VLEVMHDARA SSLDVEQDII
DIKYIYESIM HFGVDVDPQE LKQAMSLHNL WECTLARVYE TERALEPKKM QFRDHTRSEV
ENFLLKGKAV LQQFREKGPS RSGIDLQEGN RLRKEWREHL VQLQARREQL TKAEKLFDLP
LTGHPHLQQL NEELTKVETV YELYVQWVAV LKRWNRSSWK DLLLEDLQST TEEKVKQARI
LGKTHGDVQP FADIQQVITN FYSSLPLLAK LKNPALKQRH WIELMKITSK QFSIEQITLD
DFIAMELYRF VDEIDNIVVS AARELAVEKD IATVKEFWFK TEFGTVPYEP RKGEVRCHVL
SDTSEIQEAV DDNILKMQSI ANVKWAQPFM DDVKLWEKKL ATINDVIAVW IVVQMKWQYL
ESIFRGSDDI ANQLPKETTK FNELDKRFVR IMNETATSPN VDVCCNISGR LDEFRYLEER
LEECQKDLSN FLEAKRRMFP RFYFISDDEL LSILAANRAK AVQDHMLKMF DNCARIIFKN
EDDDTVCGVE SQEGERLNFE HQVRTEDTPV EEWLQCVLEE TRSSLHDNLK AGVYYYPRMP
RLDWVKKHHG MVTLTGAKVW WTHEVEDAFT AVKKGKKNGV KELSLKLTRQ LIDLVGEMDK
DIDKLYAKKI NTLIIVDVHG RDIVDRFVRD SITDVREFDW ESQLRFYWER DGDTCAIRQC
TGRFKYGYEY MGLNGRLVIT PLTDRCFMTL TQALSFYLGG APGGPAGTGK TESVKDLAKA
MAIHCVVFNC GEGLDYKAMG TIFSGLSQSG SWGCFDEFNR IELPVLSVVS EQLRSIQSAL
KTEAKEFIFG DSTIRLVPTV GVFITMNPGY AGRVELPDNL KALFRPVVMV VPDMELIAEN
MLFSEGFATA RELAKKMVTL YQLARGQLSK QHHYDWGLRA LKAVLVMAGQ LKRGAPELSE
EAVLMRALRD MNTPKFVAED EPLFKGLIGD LFPGLDPTRA PQENLSRAAS KVFKDKGFYV
DAKQVDKVVQ LYETMQTRHT SMVVGPTGGG KSTVIDCLCK SQTQLGLPTK LFVINPKAQP
TTVLYGVMDP MTRSWSDGIF SNIFRMINRP TEGGERERRY VVFDGDVDAK WVEDMNSVMD
DNKLLTLPNG ERIRLRPTSS LLFEVGDLQY ASPATVSRVG MVFLDPVNLG WRPFLHSWKL
SRPRDELETL NELVDKYIEP LINFVLEGVD GDEVSDPPKS VVPTSDLNMV RQLATMIDTV
SSQKASLEPK ALQCVFIFCC VWSFGALVTN EEDRIRFDKF LKKIAGWNMQ DVGDKFLTRF
VGSGSLPERK TMYDYFFDLE DNRWKPWHVL VRPFERPPGT KFGTLLVATP DTERNMWLLN
KVVLRRTPVM LVGKSG
//
