ID G0V2T0_TRYCI Unreviewed; 347 AA.
AC G0V2T0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 03-MAY-2023, entry version 42.
DE SubName: Full=Uncharacterized protein TCIL3000_11_14690 {ECO:0000313|EMBL:CCC95952.1};
GN ORFNames=TCIL3000_11_14690 {ECO:0000313|EMBL:CCC95952.1};
OS Trypanosoma congolense (strain IL3000).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Nannomonas.
OX NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCC95952.1};
RN [1] {ECO:0000313|EMBL:CCC95952.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IL3000 {ECO:0000313|EMBL:CCC95952.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; HE575324; CCC95952.1; -; Genomic_DNA.
DR AlphaFoldDB; G0V2T0; -.
DR VEuPathDB; TriTrypDB:TcIL3000.11.14690; -.
DR OrthoDB; 168865at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006862; P:nucleotide transport; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR044712; SLC25A32-like.
DR PANTHER; PTHR45683:SF6; CARRIER PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45683; MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|RuleBase:RU000488}.
FT TRANSMEM 100..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 36..129
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 140..241
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 252..340
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 38487 MW; BF2A0B1B8CC45800 CRC64;
MTKGDAESEA EHHGGAHRRP PQHPVASCGP RQRASSSSYS HVLASQLASA ISTTVSYPID
TLRVRFMSQD GTVQRQHNGQ TYRSICRAMD TICREEGVRA LFRGCHVAVL GAVVAWGVYM
FIYRTLCDIC LPDNGKRAGN DFTYRTLLSS VASCSCAVVC NPIWLLKTRM QIEEISSRKA
SPCPPSTTTC KGKNYASFIG GLLYAVRTDG VLSLWRGVSA QVLLGLPNAL NFPVYEAFKS
KWLDYMDRQN LYSYEACLCS TISKTAVSVV AYPIHVIKTR MQDQRSQLGN VKYISFLQSV
SVVLRSRGVA DLYRGITPSL LHSVPRLALT FVLYEKFLEA DVLRYVS
//
