ID G0V4M7_9CLOT Unreviewed; 553 AA.
AC G0V4M7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:CCC58067.1};
GN ORFNames=CAAU_0418 {ECO:0000313|EMBL:CCC58067.1};
OS Caloramator australicus RC3.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Caloramator.
OX NCBI_TaxID=857293 {ECO:0000313|EMBL:CCC58067.1, ECO:0000313|Proteomes:UP000007652};
RN [1] {ECO:0000313|EMBL:CCC58067.1, ECO:0000313|Proteomes:UP000007652}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RC3 {ECO:0000313|EMBL:CCC58067.1,
RC ECO:0000313|Proteomes:UP000007652};
RX PubMed=21421756; DOI=10.1128/JB.00193-11;
RA Ogg C.D., Patel B.K.C.;
RT "Draft genome sequence of Caloramator australicus strain RC3T, a
RT thermoanaerobe from the Great Artesian Basin of Australia.";
RL J. Bacteriol. 193:2664-2665(2011).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCC58067.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAKP01000019; CCC58067.1; -; Genomic_DNA.
DR RefSeq; WP_008907785.1; NZ_CAKP01000019.1.
DR AlphaFoldDB; G0V4M7; -.
DR STRING; 857293.CAAU_0418; -.
DR eggNOG; COG1032; Bacteria.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000007652; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR025288; DUF4080.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF18; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13311; DUF4080; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007652}.
FT DOMAIN 1..132
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 170..403
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 553 AA; 65123 MW; 3D7B02D72C3E7591 CRC64;
MKVLLIALNS KYVHSNLAIR YLRAYVNEFD VEIFEGTINE NPFNLALEIA RKKPDVVAFS
CYIWNIENIL KICGILKEIN KDITIILGGP EVSYDPKNIL QLNEYIDYII FGEGEETFKE
LLEYLSRQGK RKDLKSMKGL AFRLGEEIIV NEERPLITNL DTIPFPYDLE IPSKIVYYEA
SRGCPFSCKY CLSSTIKGVR FFSLERIKRD LKYLIDNDVK LVKFVDRTFN ANKRMAIEIW
EFLIQNSKGT KFHFEIAADL LDEDCFEVLK RAPKDLFQFE IGVQTTNETV LKNINRIMDF
ERVKNNVKRV MSMGNIHCHL DLIVGLPGED FSSFRRSFED VMDIKPDVLQ IGFLKVLKGS
PISFEAEEYG IKYSPYPPYQ VLKTKDLSFE EVVFLLKFEE VFETFYNSHI FNNTIRYFLN
KLNSYEFFSK LTIFLEENNF FKLNFDLNGK TKLLLEFLKK YEDEDIVKSL LIHDYLFTTK
KGYLPEFFKS NDEINIKDVL AENKEIIYEK LRVKDFKSVF AVKVKVDIKE DYIYGNYILV
INLLDKRFFY INM
//
