ID G0V982_NAUCC Unreviewed; 505 AA.
AC G0V982;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 03-MAY-2023, entry version 55.
DE RecName: Full=V-type proton ATPase subunit H {ECO:0000256|PIRNR:PIRNR032184};
GN Name=NCAS0A14740 {ECO:0000313|EMBL:CCC68032.1};
GN OrderedLocusNames=NCAS_0A14740 {ECO:0000313|EMBL:CCC68032.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC68032.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC68032.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase),
CC a multisubunit enzyme composed of a peripheral complex (V1) that
CC hydrolyzes ATP and a membrane integral complex (V0) that translocates
CC protons. V-ATPase is responsible for acidifying and maintaining the pH
CC of intracellular compartments. {ECO:0000256|PIRNR:PIRNR032184}.
CC -!- SUBUNIT: V-ATPase is a heteromultimeric enzyme made up of two
CC complexes: the ATP-hydrolytic V1 complex and the proton translocation
CC V0 complex. {ECO:0000256|PIRNR:PIRNR032184}.
CC -!- SIMILARITY: Belongs to the V-ATPase H subunit family.
CC {ECO:0000256|ARBA:ARBA00008613, ECO:0000256|PIRNR:PIRNR032184}.
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DR EMBL; HE576752; CCC68032.1; -; Genomic_DNA.
DR RefSeq; XP_003674411.1; XM_003674363.1.
DR AlphaFoldDB; G0V982; -.
DR STRING; 1064592.G0V982; -.
DR GeneID; 11529565; -.
DR KEGG; ncs:NCAS_0A14740; -.
DR eggNOG; KOG2759; Eukaryota.
DR HOGENOM; CLU_025709_4_0_1; -.
DR InParanoid; G0V982; -.
DR OMA; GIQLQYY; -.
DR OrthoDB; 176803at2759; -.
DR Proteomes; UP000001640; Chromosome 1.
DR GO; GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; IEA:UniProtKB-UniRule.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 1.25.40.150; V-type ATPase, subunit H, C-terminal domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR004908; ATPase_V1-cplx_hsu.
DR InterPro; IPR011987; ATPase_V1-cplx_hsu_C.
DR InterPro; IPR038497; ATPase_V1-cplx_hsu_C_sf.
DR PANTHER; PTHR10698; V-TYPE PROTON ATPASE SUBUNIT H; 1.
DR PANTHER; PTHR10698:SF0; V-TYPE PROTON ATPASE SUBUNIT H; 1.
DR Pfam; PF11698; V-ATPase_H_C; 1.
DR Pfam; PF03224; V-ATPase_H_N; 1.
DR PIRSF; PIRSF032184; ATPase_V1_H; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW ECO:0000256|PIRNR:PIRNR032184};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR032184};
KW Reference proteome {ECO:0000313|Proteomes:UP000001640};
KW Transport {ECO:0000256|PIRNR:PIRNR032184}.
FT DOMAIN 378..502
FT /note="ATPase V1 complex subunit H C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11698"
SQ SEQUENCE 505 AA; 57252 MW; D11B8DEEE4B5460A CRC64;
MTMDAKTNNT TILLDSTHFN EIRGAIRSRT VAWDALARSG EISELDASVA KKLETILIKE
NAPDGVAENL IIDESVVLPL IHLMAHAMEN DSESKFEILK SVQNLFVELF CSASFCDGTI
EFFVQNPDQL DALFKVSLVG DVQTVLISAF NLVTLLIQPE LIEKKKVSNI KMVDELLGNK
DFMGILKGYE RTDTCYVCIR LIQELMGVKQ YRSTIWSHEA DIVPVLFIIL KRAINDSNSM
NNNNSSSNNN GHSPRLVATS SNNLGIQIQY YSLLLIWLMT FNSTWANEFV NKYLSDFLNL
LKLVKITIKE KISRLSISII LQCCSTNVKG HKSIIKNLIL LGNGIPTLQS LSERKYSDEE
LREDIITLKE LLEEEYQELT SFDEYVAELD SKLLCWSPPH IDNGFWSDNI DSFKENGWKL
FKKLVNLLIE ISADHEDLNT RQNKLILQVV LNDITHVIEL LPESVDVLNK MNGKVVIMEL
LNHSDSRVKF EALKATQAMI GYTLR
//
