ID G0W517_NAUDC Unreviewed; 866 AA.
AC G0W517;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=NDAI0A07510 {ECO:0000313|EMBL:CCD22905.1};
GN OrderedLocusNames=NDAI_0A07510 {ECO:0000313|EMBL:CCD22905.1};
OS Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC
OS 0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCD22905.1, ECO:0000313|Proteomes:UP000000689};
RN [1] {ECO:0000313|EMBL:CCD22905.1, ECO:0000313|Proteomes:UP000000689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC {ECO:0000313|Proteomes:UP000000689};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; HE580267; CCD22905.1; -; Genomic_DNA.
DR RefSeq; XP_003668148.1; XM_003668100.1.
DR AlphaFoldDB; G0W517; -.
DR STRING; 1071378.G0W517; -.
DR GeneID; 11494386; -.
DR KEGG; ndi:NDAI_0A07510; -.
DR eggNOG; KOG0390; Eukaryota.
DR HOGENOM; CLU_000315_10_1_1; -.
DR OMA; FTIMYRK; -.
DR OrthoDB; 5480555at2759; -.
DR Proteomes; UP000000689; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18004; DEXHc_RAD54; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.850; SWI2/SNF2 ATPases, N-terminal domain; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000689}.
FT DOMAIN 294..482
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 633..790
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 866 AA; 98471 MW; B1B6F687D637E9E7 CRC64;
MMNLPKYENK PFKPPRKLTL TGNAKTSTVK RSISRTQITA SPLTKRTKTC ATLTETPSAL
PNQSDNNKLF TIMYRKPSMK KHKTWDKDGY AELKQSGILI FYNESGARIG RVSKIEPLLE
TIHKAGSWEV QLDYELTDTK EITKIRTLLK NNFESASITP PSTASSTASN VLPSTSKAQI
PITQLFTVQT VKKFKTVLPK PNEHTSLSTT VNQDTNSTRR NYLPVFVQTK IKNPLVMNKS
IDADVDVIVD PLISKFLRKH QREGVKFIYD CINGLSQVEA STAVVDPTQQ SMILEKNSDI
NGCLLADEMG LGKTLMTIAV IWTLYKQTPL VKNIPCSQSG VPLSGLCKKF LIICPVTLIG
NWKREFKKWL NLNRIGILTL NSNNTPEMDR NAVKNFLKVQ RTYQVLIMGY EKVLSVSAEL
TNQKNLIDML VCDEGHRLKS GTSKVLQVLK NLDVKRKILL SGTPIQNDLN EFYTIIDFIN
PGILGSFPYF KKRYMVPITR ARDTSNRYNE EILELGEERS REMIEITKQF TLRRTNSILT
EYLPPRTDII LFCKPTETQL QAFDNAIRGA KLDFNTASFN STLGLITLLK KICNSPSLIK
NDSYFTSKID HSQYQRANFN VLNSGKLMVL MSLLKHLRTN CPEEKIVIVS NYTQTLDIIE
NLLLSEQMIF CRLDGSTLPK QRDSIVMSFN RNPSTFAFLL SAKSGGVGLN LVGASRLVLF
DNDWNPSIDL QAMSRIHRDG QKRPCYIYRL ITTGCIDEKI LQRQLMKHNL SQKFLDSSIE
NTNVNDDLFD KQDLRDLFSI NHHTKSNTHD LICTCDGLGD EIQYDTEAPD SVPPNGKKCT
TWNQRVNNYQ RRSKKWTSLH KKKRQL
//
