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Database: UniProt
Entry: G0WAZ0_NAUDC
LinkDB: G0WAZ0_NAUDC
Original site: G0WAZ0_NAUDC 
ID   G0WAZ0_NAUDC            Unreviewed;       851 AA.
AC   G0WAZ0;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   05-JUL-2017, entry version 28.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   Name=NDAI0E00940 {ECO:0000313|EMBL:CCD24910.1};
GN   OrderedLocusNames=NDAI_0E00940 {ECO:0000313|EMBL:CCD24910.1};
OS   Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 /
OS   NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX   NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCD24910.1, ECO:0000313|Proteomes:UP000000689};
RN   [1] {ECO:0000313|EMBL:CCD24910.1, ECO:0000313|Proteomes:UP000000689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC   {ECO:0000313|Proteomes:UP000000689};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S.,
RA   Byrne K.P., Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type
RT   switching accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; HE580271; CCD24910.1; -; Genomic_DNA.
DR   RefSeq; XP_003670153.1; XM_003670105.1.
DR   STRING; 1071378.XP_003670153.1; -.
DR   EnsemblFungi; CCD24910; CCD24910; NDAI_0E00940.
DR   GeneID; 11498628; -.
DR   KEGG; ndi:NDAI_0E00940; -.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   KO; K02154; -.
DR   OrthoDB; EOG092C0YCY; -.
DR   Proteomes; UP000000689; Chromosome 5.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IEA:EnsemblFungi.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:EnsemblFungi.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:EnsemblFungi.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:EnsemblFungi.
DR   GO; GO:0016049; P:cell growth; IEA:EnsemblFungi.
DR   GO; GO:0043623; P:cellular protein complex assembly; IEA:EnsemblFungi.
DR   GO; GO:0006797; P:polyphosphate metabolic process; IEA:EnsemblFungi.
DR   GO; GO:0007035; P:vacuolar acidification; IEA:EnsemblFungi.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000689};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000689};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    426    450       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    471    488       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    548    566       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    578    603       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    642    659       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    745    764       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    776    799       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED      120    157       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   851 AA;  97066 MW;  37595E4084055002 CRC64;
     MSAVETVPKD EAMFRSAVMS LVQLYIPQEI ARDAVYTLGQ LGIVQFRDLN SETNSFQRTF
     VDEIRRLDNV QRQYRYFFKL LQKHNIPLYE GAIEQYDRPS NLNDANIMSQ LIVPPSTSAI
     DDHVQNAALL EQRLVQMEEA TEQIEAQKVD LEQYRIVLQS GDQFFQSGDS MALAATATVV
     DLEDTLRRSS ITINFVTGII PRDKINTFEQ ILWRVLRGNL FFKHIEIEQP IFDVKTQSYI
     AKNAFIVYSH GDLILDRIKR IAESLDAHLY EIDKNPESRS QKLLKINENL SDLYTVLQST
     TTTLESELFG IGQELNSWYQ DIAREKSTYE TLNKFNFDKN RKTLIAEGWI PEDELSFLKD
     CLVQMTSKLG VDVPSIIQVL GTNKTPPTFH RLNKFTQAFQ SICDSYGVPQ YREVNPGLPT
     IVTFPFMFAI MFGDMGHGFI MTMAALVFVL NEKKFDRMKR GEILDMAYTG RYIILFMGLF
     SMYTGFLYND IFSRSMTLFK SGWEWPEDFK AGEMLYAKKV GTYPIGIDWA WHGAENSLLF
     SNSYKMKLSI VMGFIHMTYS YMFSLVNHLH FKSMIDIVAN FIPGLLFMQG IFGYLSVCII
     YKWSVDWIGD GKAAPGLLNM IINMFLAPGT IDEELYPHQA KVQIFLLGMA LLCVPWLLLM
     KPLHFKFTHS EKKNSFPTAD DIETQALLHD ENEDEIAETE GTIAANNDSE EGEGHGEELG
     DVIIHQVIHT IEFCLNCVSH TASYLRLWAL SLAHAQLSSV LWSMTLELSF GVPGALGVFM
     TVSLFTLWFC LTIAVLVMME GTSAMLHSLR LHWVESMSKY FVGDGIPYEP FVFQYLDMET
     DVANNAGNIA A
//
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